Notes in 6 Ca & Phosphate

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Published 10/09/2024 Where does most calcium reabsorded?{{c1::PCT::nephron region}}
Published 10/09/2024 Besides the PCT, where is the 2nd largest Ca+ reabsorb site?{{c1::Thick Ascending Limb Loop of Henle}}
Published 10/09/2024 Thiazide causes {{c1::inc}} Ca+ uptake ⇒ causes decreased urine Ca+
Published 10/09/2024 Furosemide causes {{c1::decreased}} Ca+ Re-absorb ⇒ {{c1::inc}} ca+ in urine
Published 10/09/2024 Where is almost ALL phosphate reabsorbed?{{c1::PCT}}
Published 10/09/2024 Calcium in serum is carried in 3 ways:Total Ca+ = {{c1::Protein Bound}} Ca + {{c1::ionized}} Ca + {{c1::complexed}} CaTotal Ca+ can be measured by ord…
Published 10/09/2024 What is the "important" Ca+ level?{{c1::Ionized Ca+}}
Published 10/09/2024 The Serum/Total Calcium measurement needs to be "corrected" based on the patient's {{c1::albumin}} levels
Published 10/09/2024 Corrected Ca+ Equation ={{c1::  [(4 – serum albumin) x .8] + serum calcium}}
Published 10/09/2024 {{c1::Chvostek’s}} Sign ⇒ tapping on the {{c2::facial}} nerve results incontraction of {{c2::ipsi}}lateral {{c2::facial}} muscles ⇒ due to {{c2::HypoC…
Published 10/09/2024 {{c1::Trousseau’s}} sign ⇒ {{c2::carpal-pedal}} spasm occurring with{{c2::inflation of blood pressure cuff}} ⇒ due to {{c2::HypoCalcemia}}
Published 10/09/2024 {{c1::HypoCalcemia}} Clinical Signs:Chvostek’s sigTetanyTrousseau’s sigProlonged QTfinish
Published 10/09/2024 "{{c1::Stones Bones Moans and Groans}}" ⇒ symptoms of {{c2::HyperCalcemia}}
Published 10/09/2024 Vitamin D MetabolismPpl eat vitamin D3 which is called {{c1::CholeCalciferol}}⇒ this is converted by liver to 25-hydroxy-D3⇒ then convered to 1,25-hyd…
Published 10/09/2024 Where in the diet do we get Vitamin D?{{c1::Supplementation in milk}}
Published 10/09/2024 Vit D converted to 25 hydroxy Vitamin D in the{{c1::liver}} (not rate limiting
Published 10/09/2024 *1,25 dihydroxy Vitamin D – made byconversion of 25 OH D to 1,25 OH D in{{c1:: (PCT) proximal tubular}} cells mediated by 25 hydroxyVitamin D 1-alpha …
Published 10/09/2024 1,25 Dihydroxy Vitamin Dfinish {{c1::}}
Published 10/09/2024 {{c1::Rickets}} ⇒ caused by decreased 1,25 dihydroxy Vitamin D ⇒ leading to dec Ca+ absotSymptoms:age of listen 8:35Causes:Treatment:Sunligh…
Published 10/09/2024 {{c2::7 dehydrocholesterol}} ⇒ it is a {{c1::Precursor to Vit D}} ⇒ Converted in skin by sun toVitamin D
Published 10/09/2024 {{c1::PTH}} causes  Resoprtion of {{c2::calcium}} and {{c2::phosphate}} frombones.• Urinary excretion of {{c2::phosphate}}
Published 10/09/2024 Osteo{{c1::blasts}} have PTH receptors finish will be on exam*****Inc Ca+ w/ Normal/Low Phosphate*****
Published 10/09/2024 {{c1::Hyperparathyroidism}}Hypercalcemia• Normal or low serum phosphate.• Hypercalciuria– Kidney stones in some individuals– Osteoporosisfinish
Published 10/09/2024 {{c2::Fibroblast Growth Factor 23 (FGF23)}} ⇒ made by {{c1::OsteoClasts}}Decreases proximal tubular phosphatereabsorption• Decreases 1,25 hydroxy vita…
Published 10/09/2024 {{c2::Calcitonin}} ⇒→ i.e. {{c1::Lowers}} Ca and {{c1::lowers}} phosphatenhibits osteoclast activity in bone• Inhibits tubular reabsorption of calcium…
Published 10/09/2024 review {{c1::}}
Published 10/09/2024 Chronic Kidney Failure:1st problem → {{c1::Dec Phosphate Excretion}}2nd problem →3rd problem → 4th problem →**finish
Published 10/09/2024 Serum signs of Chonic Kidney DiseaseInc {{c1::Phosphate}}
Published 10/09/2024 Treating Chronic Kidney Failure1. Treat {{c1::Hyperphosphatemia}} via Diet and phosphate binders pi→ on test2. calcitriol or calcitriol analogs to mak…
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