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LE031 Thrombotic microangiopathy and Disseminated Intravascular Coagulation
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Published
10/19/2024
Microangiopathic Hemolitic Anemia (MAHA) is {{c1::a type of anemia that occurs when RBCs are destroyed (hemolysis) due to damage in small blood vessel…
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10/19/2024
Categorization of Anemia (3 size categorize and their causes){{c1::}}
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10/19/2024
Anemia categorized on reticulocyte production index{{c1::Hypoproliferative}} vs {{c1::Hyperproliferative}} (causes)
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10/19/2024
Hemolytic Anemia Categorized based on site of RBC destruction {{c1::intravascular: blood vessels}} vs {{c1::extravascular:spleen}}
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10/19/2024
Hemolytic anemia categorized by immune vs non-immune{{c1:: }}
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10/19/2024
Hemolytic anemia: Intrinsic vs Extrinsic to RBC causes{{c1::}}
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10/19/2024
Thrombocytopenia categorized based on proliferative state{{c1::decreased production}} vs {{c1::increased destruction}} vs {{c1::increased se…
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10/19/2024
Primary vs Secondary Hemostasis{{c1::}} vs {{c1::}}
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10/19/2024
Schistocytes are a marker of {{c1::RBC Fragmentation}}
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10/19/2024
Thrombotic Thrombocytopenic Purpura (TTP) has a {{c1::>90%}} mortality rate when untreated and presents with:1. {{c1::fever}}2. {{c1::MAHA}}3.…
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10/19/2024
TTP ({{c1::Thrombotic Thrombocytopenic Purpura}}) is due to {{c1::the formation of excessive platelet-vWF pluggs}} resulting from {{c1::the prese…
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10/19/2024
Clinical summary of TTP (thrombotic thrombocytopenic purpura):{{c1::}}
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10/19/2024
TTP ({{c1::Thrombotic Thrombocytopenic Purpura}}) Management involves {{c1::Plasma Exchange}}, {{c1::Immuno Supression}}, and {{c1::Ant…
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10/19/2024
What does Rituximab do? {{c1:: it is a monoclonal antibody against CD20 (a B-cell marker) to suppress the immune system (specifically antibody pr…
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10/19/2024
What is Caplacizumab?{{c1::It is a monoclonal andibody against vWF used to treat TTPWorks, but can cause acquired vWB disease}}
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10/19/2024
Hemolytic Uremic Syndrome (HUS) is comprised of {{c1::MAHA (Microangiopathic Hemolitic Anemia)}}, {{c1::Thrombocytopenia}}, and Acute Kidney…
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10/19/2024
What is the most common causes of Hemolytic Uremic Syndrome? {{c1::Shiga toxin-producing E. Coli (STEC)O157:H7 causes direct damage to renal arte…
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10/19/2024
aHUS ({{c1::atypical Hemolitic Uremic Syndrome}}) differs from HUS in that it has no {{c1::diarrhea}}It differs from TPP in that it has 1) {{c1::…
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10/19/2024
aHUS is a result of {{c1::complement-mediated endothelial cell injury (autoimmune)}} instead of a STEC infection
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10/19/2024
Treatment of aHUS is {{c1::Eculizumab}} which is a {{c1::monoclonal antibody against C5 (terminal compliment protein)}}
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10/19/2024
TPP vs HUS Clinical summary {{c1::}}
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10/19/2024
TPP vs HUS etiological summary{{c1::}}
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10/19/2024
DIC (Disseminated Intravascular coagulation) is a result of {{c1::abnormal activation of the blood clotting cascade}} along with {{c1::hyper…
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