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Renal Anat, Devel, Struc & Func
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spring-enemy-hot-east-blue-timing
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10/02/2023
functions of the kidney- regulates balance of {{c1::H2O}}, {{c1::electrolytes}}, {{c1::acid-base}}- {{c2::excretion}} of metabolic waste, H2O, drugs o…
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kidneys lie in {{c1::superior}} abdominal cavity {{c1::posterior}} to the peritoneal sac- divided into three parts→ {{c2::cortex}}: outermost region→ …
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development of renal system- the {{c1::intermediate mesoderm}} on both sides forms {{c2::urogenital}} ridge *runs parallel to future {{c3::vertebral c…
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cortex of {{c2::suprarenal}} glands secrete {{c1::steroid}} hormones (like cortisol) while medulla secretes {{c1::catecholamines}}
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{{c1::nephrons}} are the basic functioning unit for {{c2::urine}} production in the kidney
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{{c1::glomeruli}} can only be found in renal {{c2::cortex}}*not present in renal {{c2::medulla}}
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three structures that arise from {{c6::nephrogenic cord}}:- {{c4::pronephros}} is nonfunctional and regresses by end of week 4- {{c3::mesone…
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If there is a problem during development of kidneys, fetus experiences {{c2::oligohydramnios}} (deficiency in {{c1::amniotic fluid}})... which ultimat…
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polycystic kidney disease (PKD)autosomal {{c1::recessive}} PKD (ARPKD): - mutation on both copies of PKHD1 gene → lack of {{c8::fibrocystin}} protein …
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medullary {{c2::sponge}} kidney- present at birth but asymptomatic, discovered in adulthood- abnormal induction of metanephric {{c1::blastem…
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multicystic {{c7::dysplastic}} kidney- non-inherited congenital kidney disease where {{c1::ureteric buds}} fail to induce differentiation of…
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10/10/2023
{{c8::medullary}} cystic kidney disease*aka as autosomal dominant {{c1::tubulointerstitial}} kidney disease becuase cyst development is actually …
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renal {{c3::agenesis}}- ureteric bud fails to induce development of {{c1::metanephric blastema}} → either one or both kidneys do not develop*reas…
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{{c2::duplex}} collecting system- ureteric bud either {{c1::splits}} or {{c1::arises twice}} from mesonephric duct - presents differently ba…
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posterior urethral valves (PUV)- a congenital disorder in genetic {{c1::males}}: abnormal fusion of mesonephric duct and cloaca → formation of me…
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{{c1::horshoe}} kidney- the two kidneys {{c2::fuse}} together (along inferior poles) during fetal development, forming a {{c3::fibrous isthmus}}-…
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kidneys secrete {{c1::erythropoietin}} hormone → increases production of RBCs
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{{c1::nephrons}} are found at the junction of the renal cortex and renal medulla
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{{c1::Juxtaglomerular}} cells ({{c1::JG}} cells) are cells in the kidney that synthesize, store, and secrete the enzyme {{c2::renin}}*{{c3::macul…
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