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The Cervix in Health and Disease
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Last Update
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Published
03/15/2025
What is the name of the opening between the uterus and the cervical canal?
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03/15/2025
What is the name of the opening between the cervical canal and the vagina?
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What part of the cervix connects the internal os to the external os?
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Where is the cervix located in relation to the uterus?
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What is the shape of the external os in a nulliparous female?
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What is the shape of the external os in a parous female?
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What structural change occurs to the cervix during pregnancy but to a lesser extent than the uterus?
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What forms in the cervix during pregnancy as a protective barrier against infection?
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What condition occurs when glandular cells from inside the cervical canal grow onto the outside of the cervix?
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What is the name of the service notified if a woman opts out of cervical screening?
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If an individual tests hrHPV negative after the initial screening, what is the next step?
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After how many consecutive inadequate or unavailable cytology tests should an individual be referred to colposcopy?
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If a colposcopy examination is inadequate, what is the next step?
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What is the management if a colposcopy examination is adequate but shows no CIN on biopsy or colposcopic impression?
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Tumors of the cervix most commonly arise at which anatomical zone?
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Which two high-risk HPV types account for approximately 70% of cervical cancer cases?
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What are the two key tumor suppressor proteins inhibited by HPV E6 and E7 proteins?
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In LSIL, dysplastic changes are limited to which part of the squamous epithelium?
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What is the key histological feature seen in the superficial layers of LSIL?
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In HSIL (CIN III), what is the extent of dysplasia within the epithelium?
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What is the most common type of invasive cervical carcinoma?
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What percentage of invasive cervical carcinomas are adenocarcinomas?
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Which anatomical zone is the common site of invasive cervical carcinoma development?
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Which of the following structures is part of the cervix?
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Which factor does NOT influence the size and shape of the cervix?
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Which of the following is NOT a physiological change of the cervix during pregnancy?
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Cervical ectropion is most commonly related to which hormone?
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Which of the following is NOT a common symptom of cervical ectropion?
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Which of the following conditions is classified as a precancerous cervical disease?
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If a woman tests hrHPV positive during initial screening, what is the next test performed?
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What is the correct step if cytology is abnormal after an initial hrHPV-positive result?
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What happens if an individual has two consecutive inadequate or unavailable cytology samples?
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If the first cytology after a positive hrHPV test is negative, when is the next screening?
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If the initial colposcopy is inadequate and the patient has hrHPV-positive results with low-grade cytology, what is the recommended next step?
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What is the appropriate next step if an individual has hrHPV-positive results with high-grade cytology after an inadequate colposcopy?
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After treatment for CGIN with complete excision margins, what is the recall schedule?
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If a cytology result is abnormal after a positive hrHPV test, what is the next step?
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Which of the following is not a predisposing factor for cervical cancer?
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What type of cells does HPV primarily infect in the cervix?
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What is the first cellular lesion that can develop from persistent HPV infection?
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Which type of squamous intraepithelial lesion (SIL) is considered a high risk for progression to carcinoma?
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Which factor does not predispose an individual to persistent HPV infection?
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Which histological feature distinguishes CIN II from CIN III?
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Which histological change is absent in HSIL (CIN III)?
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Which method is used to highlight cervical lesions during colposcopy?
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Which factor is not considered a risk for progression from SIL to invasive carcinoma?
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What is the worldwide annual death toll from cervical cancer?
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Which method is considered the most reliable for monitoring cervical cancer progression?
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Arrange the following structures of the cervix in order from superior to inferior:
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Place the diagnostic methods for cervical pathology in the typical order of use:
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Arrange the correct sequence for handling a woman who initially tests hrHPV positive but cytology negative.
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Place the following management steps in order after a CIN2/3 result post-colposcopy:
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Arrange the correct pathway for a CGIN result with positive hrHPV after initial treatment:
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Arrange the following in the correct order regarding the progression of HPV-related cervical disease:
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Arrange the following steps for monitoring the progression of cervical lesions:
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True or false: The Cervix in Health and Disease 1
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True or false: The Cervix in Health and Disease 2
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True or false: The Cervix in Health and Disease 3
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Produces mucus | Acts as a barrier | Holds pregnancy in place | Effaces and dilates
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03/15/2025
Chlamydia trachomatis | Trichomonas vaginalis | Neisseria gonorrhoeae | Mycoplasma genitalium | Human papilloma virus
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03/15/2025
Opt-out of screening | Initial hrHPV negative | Initial hrHPV positive, cytology negative | Cytology abnormal | Third consecutive hrHPV positive
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Inadequate colposcopy + hrHPV-positive, low-grade cytology | Inadequate colposcopy + hrHPV-positive, high-grade cytology | Third consecutive hrHPV-pos…
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Inadequate exam + low-grade cytology | Inadequate exam + high-grade cytology | CIN1 confirmed | CIN2 or CIN3 | CGIN with complete excision margins | T…
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E6 protein | E7 protein | HPV DNA replication | Persistent HPV infection
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LSIL | Persistent LSIL | HSIL | Biopsy-confirmed HSIL follow-up
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Nests of squamous cells with desmoplastic stroma | Glandular cell formation | Originates in the transformation zone
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Status
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