Notes in Week 16 - Rheumatology series

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Published	11/19/2024	What are the two sporadic risk factors for CPPD?{{c1::Advanced age and hypothyroidism}}
Published	11/19/2024	{{c1::ANK}} is an ATP transporter protein that regulates extracellular pyrophosphate levels and is mutated in familial CPPD
Published	11/22/2024	4 year old HM presents with 2 months of worsening swelling in L big toe at base. No redness, pain initially, but now tight and even with some skin bre…
Published	11/22/2024	The goal for the treatment of chronic gout is to get the serum urate below {{c1::6mg/dl}}
Published	11/22/2024	What is the main urostatic agent for lowering urate in gout?{{c1::Allopurinol}}
Published	11/22/2024	CC: finger pain, swelling ◼ HPI: 84 yo WF with known OA complains of chronic aching and swelling of DIPs – gradually over past year; episodes of warmt…
Published	11/22/2024	What is the best treatment option for an acute gout attack?{{c1::Corticosteroids}}
Published	11/22/2024	What is an example of a secondary cause of hyperuricemia?{{c1::Psoriasis}}
Published	11/22/2024	What component of diet for the development of gout decreases risk?{{c1::Diary consumption}}
Published	11/22/2024	{{c2::Gout}} is associated with HLA-{{c1::B58}}
Published	11/22/2024	During a gout attack, will the serum uric acid be low, normal, or high?{{c1::Normal or low}}
Published	11/22/2024	A 54 yo man presents with 6 months: spontaneous chronic aching, stiffness and pain in the knuckles with some warmth and tenderness. PMH: “liver inflam…
Published	11/22/2024	CC: “my back hurts” HPI: 25 yo male with 4 mos of bilateral buttock and lower back pain. Dull, achy but can be sharp with coughing, sneezing, bending;…
Published	11/22/2024	CC: “my gout is acting up for the past couple weeks” HPI: ▪ 64 yo man previously diagnosed “gout”: intermittent swelling of various toes and achilles …
Published	11/22/2024	ID pattern: {{c1::Candle wax pattern}}
Published	11/22/2024	18 yo Caucasian woman presents with 2 wks of abdominal pain, hematochezia, joint swelling – ankles and knees with worsening rash.img shows: palpable p…
Published	11/22/2024	47 yo man with recently diagnosed pancreatic ca presents with dusky purplish tone to tips of fingers and toes in past month – mod aching and numbness.…
Published	11/22/2024	What are three important criteria for classification of polyarteritis nodosa (PAN)?{{c1::Livedo reticularis}}{{c1::Testicular pain}}{{c1::HBV}}
Published	11/22/2024	What are the important criteria for Wegener's or Granulomatosis with Polyangiitis (GPA)?{{c1::Nasal/oral inflammation}}{{c1::Abnormal chest radiograph…
Published	11/22/2024	What are the two treatments for GPA?{{c1::Rituximab and Avacopan}}
Published	11/22/2024	Which ANCA for GPA and MPA?{{c1::C-ANCA and P-ANCA}}
Published	11/22/2024	What is mechanism of action for avacopan?{{c1::Inhibits C5a}}
Published	11/22/2024	What are the important criteria for EGPA (Churgg-Strauss)?{{c1::Asthma}}{{c1::Eosinophilia >10%}}{{c1::Pulmonary infiltrates}}
Published	11/22/2024	Syndrome with pelvic and shoulder girdle aching + morning stiffness?{{c1::Polymyalgia rheumatica}}
Published	11/23/2024	{{c1::Psoriatic arthritis}} can present with "{{c2::Ray phenomenon}}," which is characterized by inflammation of the {{c3::MCP, PIP, and DIP}} jo…
Published	11/23/2024	{{c1::Löfgren syndrome}} is a subtype of {{c2::sarcoidosis}} that presents with triad of:- Hilar lymphadenopathy- Erythema nodosum- Art…
Published	11/23/2024	Löfgren syndrome is a subtype of sarcoidosis that presents with a triad of:- {{c1::Hilar lymphadenopathy}}- {{c1::Erythema nodosum…
Published	11/23/2024	Treatment for rheumatoid arthritis is:Short-term: {{c1::DMARDs ± glucocorticoids}}Long-term: {{c1::DMARDs}}
Published	11/23/2024	Which DMARD(s) are used to treat rheumatoid arthritis in a patient with chronic HCV?{{c1::Hydroxychloroquine}}
Published	11/23/2024	Which DMARD(s) are used to treat rheumatoid arthritis in a pregnant patient?{{c1::Hydroxycholoriquine or sulfasalazine}}
Published	11/23/2024	Which DMARD(s) are used to treat rheumatoid arthritis in a patient with breast cancer?{{c1::Rituximab}}
Published	11/23/2024	Which DMARD(s) are used to treat rheumatoid arthritis in a patient with COVID pneumonia?{{c1::Tocilizumab}}
Published	11/26/2024	"Jaccoud's" arthritis is commonly seen in patient with {{c1::systemic lupus erythematosus}} and is characterized by {{c2::reversible::r…
Published	11/26/2024	Examination of the fingers in patients with systemic lupus erythematosus can present with dilated {{c1::nailfold capillaries}}
Published	11/26/2024	Systemic lupus erythematosus can accelerate the development {{c1::atherosclerosis::cardiac}}
Published	11/26/2024	Which immunosuppressive agents should be avoided in treating pregnant patients with SLE due to their teratogen…
Published	11/26/2024	Which antibody increases the risk for the development of neonatal lupus and complete heart block?{{c1::anti-SSA (anti-Ro)}}
Published	11/26/2024	{{c1::Poly}}myositis targets myofibers
Published	11/26/2024	{{c1::Dermato}}myositis targets blood vessels
Published	11/26/2024	{{c1::Creatine phosphokinase (CPK)}} is the most sensitive enzyme in detecting polymyositis and dermatomyositis
Published	11/26/2024	These images depict {{c1::shawl sign}} in dermatomyositis
Published	11/26/2024	The "mechanic's hands" seen in dermatomyositis is also known as {{c1::anti-synthetase syndrome}}
Published	11/26/2024	Calcinosis cutis can present in limited scleroderma as well in {{c1::pediatric dermatomyositis}}
Published	11/26/2024	Myopathic syndromes may be associated with anti-Jo-1, anti-Mi-2, {{c1::anti-TIF1-γ}}, {{c1::anti-NXP-2}}, and {{c1::anti-HMGCR}} antibo…
Published	11/26/2024	First-line treatment for dermatomyositis and polymyositis is {{c1::glucocorticoids and immunosuppressive agents (methotrexate…
Published	11/26/2024	What classes of drugs can be used to treat the vasoconstriction associated with scleroderma?{{c1::Endothelin antagonists and prost…
Published	11/26/2024	Sjögren syndrome results in an autoimmune response against {{c1::muscarinic}} receptors
Published	12/10/2024	asf{{c1::d}}
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