Notes in Pregnancy

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Published	04/01/2024	Best ASM for woman on contraceptives and why?{{c1::Keppra}}, gabapentin, lamotrigine, tiagabine dont enhance cytochrome p450
Published	04/01/2024	propofol infusion syndrome (PRIS): {{c1::acute bradycardia and asystole}} PLUS :RhabdoMetabolic acidosis HLDEnlarged or fatty liverMore common in {{c2…
Published	04/01/2024	Stroke is a leading cause of maternal morbidity and mortality, and most fatal strokes are {{c1::preventable}}.
Published	04/01/2024	The highest-risk time period for maternal stroke is the {{c1::immediate postpartum period}}.
Published	04/01/2024	Migraine and hypertensive disorders of pregnancy, including {{c1::gestational hypertension}} and {{c2::preeclampsia}}, are major risk factors for mate…
Published	04/01/2024	Many catastrophic maternal strokes could be avoided with targeted prevention efforts, early recognition of warning signs, and rapid evaluation of {{c1…
Published	04/01/2024	Stroke is a major cause of severe maternal morbidity and mortality in the United States, accounting for {{c1::1::#}} in 12 deaths in women who are pre…
Published	04/01/2024	Complications of hormonal induction, such as {{c1::ovarian hyperstimulation syndrome::condition}}, are associated with up to a 10% risk of {{c2::throm…
Published	04/01/2024	{{c1::Cesarean delivery:: Delivery method}} has been associated with a higher risk of postpartum maternal stroke.
Published	04/01/2024	Cesarean delivery carries a risk of {{c1::postsurgical complications}}, such as deep venous thrombosis and infection, both of which increase stroke ri…
Published	04/01/2024	Postpartum choriocarcinoma is associated with a high risk of {{c1::thrombotic events}} due to hypercoagulability.
Published	04/01/2024	{{c1::Peripartum cardiomyopathy::Condition}} is defined as new-onset heart failure within 1 month before to 5 months after delivery without another ex…
Published	04/01/2024	Approximately half of maternal strokes are {{c1::hemorrhagic, including subarachnoid hemorrhage, intracerebral hemorrhage, and hemorrhagic venous infa…
Published	04/01/2024	Most studies show a steady increase in the incidence of maternal stroke over the past {{c1::30::#}} years.
Published	04/01/2024	The highest risk of maternal stroke occurs in the {{c1::peripartum}} and immediate {{c2::postpartum}} periods, from approximately 1 day before to 2 we…
Published	04/01/2024	The risk of maternal thromboembolic events and intracerebral hemorrhage remains elevated up to {{c1::12::#}} weeks after delivery; a Taiwanese populat…
Published	04/01/2024	Pregnant and postpartum patients who are {{c1::Black::race}} experience disproportionately high rates of stroke and mortality regardless.
Published	04/01/2024	The incidence of stroke in women during pregnancy and the postpartum period is approximately {{c1::triple::triple or double}} the incidence of stroke …
Published	04/01/2024	Volume expansion occurs throughout pregnancy, resulting in physiologic dilutional anemia and decreased levels of {{c1::some clotting factors, such as …
Published	04/01/2024	In addition, pregnancy produces an adaptive shift to a {{c1::procoagulant}} state, with increased levels of von Willebrand factor, factor V, factor VI…
Published	04/01/2024	Pregnancy is associated with the {{c1::Virchow triad}} (venous stasis, hypercoagulability, and delivery-associated vascular damage), contributing to a…
Published	04/01/2024	In pregnant or postpartum patients, {{c1::PRES}} is highly associated with eclampsia, and nearly 100% of patients with eclampsia show signs of PRES on…
Published	04/01/2024	{{c1::RCVS}} is a syndrome of transient, multifocal, segmental nonvasculitic vasospasm of the large and medium-sized cerebral arteries, typically pres…
Published	04/01/2024	RCVS is typically triggered by an event or drug such as orgasm, sympathomimetic or serotonergic medications (eg, cocaine, antidepressants), or the {{c…
Published	04/01/2024	{{c1::Cerebral venous thrombosis::Condition}} risk factors include obesity, preeclampsia, infection, dehydration (as seen with hyperemesis gravidarum)…
Published	04/01/2024	Treatment of cerebral venous thrombosis typically consists of therapeutic anticoagulation for {{c1::3 to 12::___ to ___}} months or until recanalizati…
Published	04/01/2024	{{c2::Migraine::Condition}} has been associated with a {{c1::15::#}}-fold increase in risk of maternal stroke in multiple studies. This is an alarming…
Published	04/01/2024	Pregnant or postpartum women who develop cerebral venous thrombosis should be evaluated for underlying {{c1::hypercoagulable disorders}}; pregnancy sh…
Published	04/01/2024	Migraine is associated with increased risk of {{c1::preeclampsia}} and a 15-fold increase in risk of {{c2::maternal stroke}}.
Published	04/01/2024	{{c1::Unfractionated heparin::Anticoagulant}} is safe during pregnancy and lactation.
Published	04/01/2024	{{c1::Warfarin::Medication}} is teratogenic, particularly between 6 and 12 weeks gestation; can consider in rare cases (eg, mechanical heart valve) af…
Published	04/01/2024	The use of {{c1::low-dose aspirin}} starting at 12 weeks of gestation is recommended in those with one or more high-risk factors or two or more modera…
Published	04/01/2024	Systolic blood pressure ≥140 mm Hg or diastolic blood pressure ≥90 mm Hg on two occasions at least {{c1::4}} hours apart is a defining characteristic …
Published	04/01/2024	HELLP ({{c1::hemolysis, elevated liver enzymes, and low platelets}}) syndrome
Published	04/01/2024	Preeclampsia is also highly associated with {{c1::peripartum cardiomyopathy}}, which, in turn, can lead to acute cardioembolic strokes.
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