Notes in Pharm 116

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Status	Last Update	Fields
Published	09/15/2023	(1-letter symbol)
Published	09/15/2023	pH > pKa: equilibrium shift to {{c1::Un-protonated (less H)}} molecule.
Published	09/15/2023	-O- (linkage name)
Published	09/15/2023	{{c1::Isoelectric point (pI)}}: the pH at which a molecule carries no net electric charge (i.e. total charge = 0)
Published	09/15/2023	(functional group)
Published	09/15/2023	The group R-COOH has pKa ~ {{c1::4.5}}
Published	09/15/2023	Hydrogen bonds have a bond strenght of ~{{c1::20}} kJ*mol-1.
Published	09/15/2023	Water is a {{c1::polar}} molecule that is {{c1::sp3}} hybridized shaped {{c1::tetrahedrally}}.
Published	09/15/2023	(1-letter symbol)
Published	09/15/2023	(functional group)
Published	09/15/2023	pH = pKa: {{c1::50:50 (Protonated : De-protonated)}}
Published	09/15/2023	Around {{c1::70%}} of mass of human body is water
Published	09/15/2023	How does Entropy change affect Gibbs Free Energy Equation?
Published	09/15/2023	(Name)
Published	09/15/2023	(3 letter symbol)
Published	09/15/2023	{{c1::Amphiphlies}} are hydrophobic and hydrophilic.
Published	09/15/2023	(functional group)
Published	09/15/2023	(1-letter symbol)
Published	09/15/2023	Water can form {{c1::4}} hydrogen bonds because it has {{c1::2}} lone pairs on oxygen and {{c1::2}} hydrogens.
Published	09/15/2023	(3-Letter symbol)
Published	09/15/2023	(1-letter symbol)
Published	09/15/2023	{{c1::Un-ionized}} molecules are more {{c2::lipophilic}}.
Published	09/15/2023	All amino acids derived from proteins are {{c1::Chiral}} (except Glycine) and have the {{c1::L}}-Stereochemistry.
Published	09/15/2023	bc98fa7db10741c4983472d5ca7da494-ao-3
Published	09/15/2023	(functional group)
Published	09/15/2023	{{c1::Ionized}} molecules: having (+) or (-) charge (more {{c2::hydrophilic}})
Published	09/15/2023	{{c1::pH}} is the measure of acidity or basicity of an aqueous solution.
Published	09/15/2023	&   (linkage & group name)
Published	09/15/2023	{{c1::Sickle cell disease}}: results from an error in just one amino acid of hemoglobin.
Published	09/15/2023	(group name)
Published	09/15/2023	Ionic interactions have a bond strenght of ~{{c1::80}} kJ*mol-1.
Published	09/15/2023	How does Enthalpy change affect Gibbs Free Energy Equation?
Published	09/15/2023	(Name)
Published	09/15/2023	(linkage name)
Published	09/15/2023	A protein is a polymer of {{c1::amino acids}} that become active by twisting and folding into their {{c1::final/native conformation}}.
Published	09/15/2023	{{c1::Solubility}} depends on ability of a solvent to interact with a solute more strongly then solute particles interact with each other.
Published	09/15/2023	Covalent bonds have a bond strenght of ~{{c1::400}} kJ*mol-1.
Published	09/15/2023	(functional group)
Published	09/15/2023	c4b239dab163436187c1cd807550b490-ao-1
Published	09/15/2023	-SH (group name)
Published	09/15/2023	(3-Letter Symbol)
Published	09/15/2023	(Name)
Published	09/15/2023	d9261bb973ad48cc940f9bc13d9451cb-ao-3
Published	09/15/2023	(functional group)
Published	09/15/2023	In Gibbs Free Energy equation:Negative value means {{c1::spontaneous}} Zero value means {{c1::equilibrium}}Positive value means {{c1::nonspontane…
Published	09/15/2023	(group name)
Published	09/15/2023	Water can form hydrogen bonds with:1. {{c1::Hydroxyl}} groups (-OH)2. {{c1::Keto}} groups (R=O)3. {{c1::Carboxylate}} ions (COO-)4. {{c1::Ammonium}} i…
Published	09/15/2023	(3-Letter symbol)
Published	09/15/2023	(1-letter symbol)
Published	09/15/2023	(Name)
Published	09/15/2023	(group name)
Published	09/15/2023	(group name)
Published	09/15/2023	d9261bb973ad48cc940f9bc13d9451cb-ao-2
Published	09/15/2023	(Name)
Published	09/15/2023	7391fa81916441d98fe9632d5f77648a-ao-2
Published	09/15/2023	ROR (functional group)
Published	09/15/2023	(1-letter symbol)
Published	09/15/2023	Name of equation:
Published	09/15/2023	(Name)
Published	09/15/2023	(3-letter symbol)
Published	09/15/2023	bc98fa7db10741c4983472d5ca7da494-ao-2
Published	09/15/2023	(Name)
Published	09/15/2023	(group name)
Published	09/15/2023	(functional group)
Published	09/15/2023	(linkage name)
Published	09/15/2023	{{c1::Hydrophobic Effect}} is tendency of water to minimize its contacts with hydrophobic molecules.
Published	09/15/2023	Measurement of an atom is in {{c1::angstrom}} which is equal to {{c1::10-10}} meters.
Published	09/15/2023	Normal metabolic activity requires > {{c1::65% water}}.
Published	09/15/2023	pH < pKa: equilibrium shift to {{c1::Protonated (more H)}} molecule.
Published	09/15/2023	Weakly acidic {{c1::Hydrogen donor}} group contain: O-H, N-H, S-H
Published	09/15/2023	(group name)
Published	09/15/2023	Typical bond angle of water molecule is {{c1::104.5o}}.
Published	09/15/2023	(functional group)
Published	09/15/2023	c4b239dab163436187c1cd807550b490-ao-2
Published	09/15/2023	bc98fa7db10741c4983472d5ca7da494-ao-1
Published	09/15/2023	R-S-S-R (functional group)
Published	09/15/2023	London dispersion forces have a bond strenght of ~{{c1::0.3}} kJ*mol-1.
Published	09/15/2023	-S-S- (linkage name)
Published	09/15/2023	RSH (functional group)
Published	09/15/2023	Dipole-dipole interaction have a bond strenght of ~{{c1::9.3}} kJ*mol-1.
Published	09/15/2023	(functional group)
Published	09/15/2023	(Name)
Published	09/15/2023	Water is an excellent solvent for {{c1::Hydrophilic}} material.
Published	09/15/2023	(1-letter symbol)
Published	09/15/2023	The lower the pKa the {{c1::stronger}} the acid.
Published	09/15/2023	How does Temperature relate to Gibbs Free Energy Equation?
Published	09/15/2023	(3-Letter symbol)
Published	09/15/2023	The lower the pH the more {{c1::acidic}} the aqueous solution.
Published	09/15/2023	(3-Letter symbol)
Published	09/15/2023	(group names)
Published	09/15/2023	Water is a poor solvent for {{c1::Hydrophobic}} materials.
Published	09/15/2023	(functional group)
Published	09/15/2023	The group R1R2NH has a pKa ~{{c1::9}}.
Published	09/15/2023	(functional group)
Published	09/15/2023	For the equation: pKa=-logKa ,Ka is the {{c1::acid dissociation constant}}, which is a quantitative measure of the strength of an acid.
Published	09/15/2023	O,N,or S are weakly basic {{c1::Hydrogen acceptor}} atoms.
Published	09/15/2023	(group name)
Published	09/15/2023	Why is protein structure important?1. {{c1::Life}}2. {{c1::Disease}}3. {{c1::Pharmaceuticals}}
Published	09/15/2023	(functional group)
Published	09/15/2023	7391fa81916441d98fe9632d5f77648a-ao-1
Published	09/15/2023	d9261bb973ad48cc940f9bc13d9451cb-ao-1
Published	09/15/2023	(3-letter symbol)
Published	09/15/2023	(1-letter symbol)
Published	09/15/2023	(Name)
Published	09/15/2023	(3-Letter symbol)
Published	09/15/2023	(1-letter symbol)
Published	09/15/2023	(name)
Published	09/15/2023	(3-letter sumbol)
Published	09/15/2023	(1-letter symbol)
Published	09/15/2023	(Name)
Published	09/15/2023	(3-letter symbol)
Published	09/15/2023	(1 letter symbol)
Published	09/15/2023	(Name)
Published	09/15/2023	(3 letter symbol)
Published	09/15/2023	(1 letter symbol)
Published	09/15/2023	(Name)
Published	09/15/2023	(3 letter symbol)
Published	09/15/2023	(1 letter symbol)
Published	09/15/2023	(Name)
Published	09/15/2023	(3 letter symbol)
Published	09/15/2023	(1 letter symbol)
Published	09/15/2023	(Name)
Published	09/15/2023	(3 letter symbol)
Published	09/15/2023	(1 letter symbol)
Published	09/15/2023	(Name)
Published	09/15/2023	(3 letter symbol)
Published	09/15/2023	(1 letter symbol)
Published	09/15/2023	(Name)
Published	09/15/2023	(3 letter symbol)
Published	09/15/2023	(1 letter symbol)
Published	09/15/2023	(Name)
Published	09/15/2023	(3 letter symbol)
Published	09/15/2023	(1 letter symbol)
Published	09/15/2023	(Name)
Published	09/15/2023	(3 letter symbol)
Published	09/15/2023	(1 letter symbol)
Published	09/15/2023	(Name)
Published	09/15/2023	(3 letter symbol)
Published	09/15/2023	(1 letter symbol)
Published	09/15/2023	(pKa of side chain)
Published	09/15/2023	(pKa)
Published	09/15/2023	Cysteine is unique because it can form {{c1::Disulfide bonds}}.These bonds are formed when t{{c1::wo thiol groups are oxidized}}.
Published	09/15/2023	(pka)
Published	09/15/2023	(pka)
Published	09/15/2023	(pka)
Published	09/15/2023	(pka)
Published	09/15/2023	(pka)
Published	09/15/2023	Both neutral and protonated forms of {{c1::histidine}} are present at pH 7.0 since its pKR is close to 7.0.
Published	09/15/2023	Process of protein synthesis
Published	09/15/2023	Peptide bonds is formed in a {{c1::condensation}} reaction. It forms a {{c1::CO-NH}} bond with elimination of water to produce a dipeptide.
Published	09/15/2023	Amino acids in polypeptides are referred to as {{c1::amino acid residues}}.
Published	09/15/2023	Polypeptides are {{c1::Linear}} (not branched) polymers.
Published	09/15/2023	Glutathione consists of 3 amino acids {{c1::(Glu-Cys-Gly)}} that undergo reduction and elimination of water to form {{c1::GSSG}}.
Published	09/15/2023	Bonding in GSH to form GSSG occurs due to what amino acid: {{c1::Cys}}
Published	09/15/2023	Physiological use of GSH is to {{c1::remove toxic, reactive oxygen from the body by reducing the product}}
Published	09/15/2023	Green Fluorescent Protein (GFP) consists of 3 amino acids: {{c1::Ser-Tyr-Gly}}A special note about this protein is that it can cyclize.
Published	09/15/2023	An average hydrogen bond length is {{c1::0.958 (~1)}} angstrom.
Status	Last Update	Fields