Notes in Thorax

To Subscribe, use this Key

Status	Last Update	Fields
Published	02/18/2024	What are the controversies around the utility of adjuvant radiotherapy for thymoma?
Published	02/18/2024	What are the indications for radiation therapy in thymoma?
Published	02/18/2024	What are the indications for radiation therapy in thymoma?
Published	02/18/2024	Regarding thymoma: reported macroscopic disease remains across a broad front at the level of the aortic arch. A decision is made to treat with radiati…
Published	02/18/2024	Discuss the role of radiation therapy in malignant pleural mesothelioma.
Published	02/18/2024	Describe the options that are available for the management of pleural effusions in the setting of malignant mesothelioma? What are the advantages and …
Published	02/18/2024	Describe the assessment and management of shortness of breath in a palliative patient
Published	02/18/2024	An asymptomatic 55-year-old man is diagnosed with non-small cell lung cancer (NSCLC). Staging investigations at diagnosis reveal a right peri-hilar 4c…
Published	02/18/2024	Discuss systemic therapies which may be useful for treating brain metastases in NSCLC. (4)
Published	02/18/2024	Describe the histopathogenesis of radiation pneumonitis
Published	02/18/2024	Pathogenesis of radiation pneumonitisRadiation induces a loss of the {{c1::alveolar barrier function}} by destroying epithelial and endothelial cells.…
Published	02/18/2024	Histopathogenesis of radiation fibrosis:Develops following prolonged {{c1::inflammatory state}} (radiation pneumonitis). This process is mediated by c…
Published	02/18/2024	Using a table compare and contrast the macroscopic, microscopic and immunohistochemical features that differentiate Non Small Cell Lung Adenocarcinoma…
Published	02/18/2024	In lung adenocarcinoma - Discuss and describe the commonly tested molecular/genomic changes and what is their significance?
Published	02/18/2024	EGFR: Mutations in the epidermal growth factor receptor (EGFR) tyrosine kinase are observed in approximately{{c1:: 15% }}of NSCLC adenocarci…
Published	02/18/2024	ALK: Rearrangements involving the anaplastic lymphoma kinase (ALK) tyrosine kinase are present in approximately {{c1::4 percent}} of NSCLC adenoc…
Published	02/18/2024	ROS1: c-ROS oncogene 1 (ROS1) is a receptor tyrosine kinase that acts as a driver oncogene in {{c1::1 to 2 percent }}of NSCLCs via a genetic tran…
Published	02/18/2024	Risk factors for mesothelioma
Published	02/18/2024	Describe the main histological subtypes and immunohistochemistry of mesothelioma.
Published	02/18/2024	Discuss the potential causes and manifestations of hypercalcaemia in a lung cancer patient
Published	02/18/2024	A 76 year old lady was treated with concurrent chemoradiotherapy (60Gy/30#) two years ago for a Stage IIIA adenocarcinoma of the lung, involving the r…
Published	02/18/2024	What are the systemic treatment options for disseminated metasatic NSCLC? What factors would you use to decide the most appropriate one?
Published	02/18/2024	In the setting of NSCLC with endobronchial progression and occluson of the airway -Discuss the various local management options, including the advanta…
Published	02/18/2024	A 56 year old woman presents with a two week history of haemoptysis and shortness of breath. A CT scan of the chest shows a 3cm right middle lobe mass…
Published	02/18/2024	In general, what is the role of surgery in the curative management of patients with stage 3a (N2) disease. Include in your answer indications and cont…
Published	02/18/2024	A 56 year old woman presents with a two week history of haemoptysis and shortness of breath. A CT scan of the chest shows a 3cm right middle lobe mass…
Published	02/18/2024	You have been asked to provide an opinion about the value of setting up a population screening program for lung cancer.     a. What adv…
Published	02/18/2024	List differentials for an incidental lung nodule
Published	02/18/2024	What investigations can be used to establish a tissue diagnosis for a solitary lung nodule? What are the benefits and limitations of each investigatio…
Published	02/18/2024	With regard to Stereotactic Ablative Body Radiation Therapy (SABR) for lung cancer:   i What are the general principles of SABR for lung tum…
Published	02/18/2024	What are the indications and limitations of SABR for lung cancer treatment?
Published	02/18/2024	Discuss the relationship between cigarette smoking and lung cancer and its management. (2)
Published	02/18/2024	A fit 62 year old woman is found to have a 4cm right lower lobe mass and a 10cm mediastinal mass. Biopsy confirms small cell lung cancer. She has limi…
Published	02/18/2024	Describe your preferred radiation therapy technique and dose fractionation schedule. Your answer should include chemotherapy details. (2)
Published	02/18/2024	The patient is planned for 3D conformal radiation therapy to be given with the first cycle of chemotherapy but the lung DVH constraints cannot be met.…
Published	02/18/2024	In the definitive treatment of LS-SCLC, what is the likelihood of this patient developing Grade 3 or 4 oesophagitis? How would you manage this?&n…
Published	02/18/2024	Lung adenocarcinoma vs SCC - Compare the epidemiology and aetiology
Published	02/18/2024	Lung adenocarcinoma vs SCC - Compare the macro and micro features
Published	02/18/2024	Lung adenocarcinoma vs SCC - compare gene mutations of therapeutic importance
Published	02/18/2024	Comparing adenoarcinoma and SCC of the lung - Biological behaviour
Published	02/18/2024	Lung adenocarcinoma vs SCC - Compare IHC differences
Published	02/18/2024	Lung adenocarcinoma DDx cheat sheet
Status	Last Update	Fields