Notes in 02_Spinal Stroke and B12 Deficient Myelopathy

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Published	02/10/2024	Presentation of {{c2::Spinal Stroke/Infarction}} {{c1::Onset: sudden to several hours}} {{c1::Back/Radicular pain}} {{c1::Paraparesis}} {{c1::Numbness…
Published	02/10/2024	Spinal Stroke/Infarction usually affects the {{c1::anterior spinal}} artery
Published	02/10/2024	Blood Supply to Spinal Cord{{c1::Anterior spinal artery (branch of vertebral artery) }}{{c1::Posterior spinal artery (branch of vertebral artery …
Published	02/10/2024	{{c1::B12 Deficient Myelopathy}} is {{c2::a myelopathy resulting from vitamin B12 deficiency, also known as Subacute Combined Degeneration of the Cord…
Published	02/10/2024	Presentation of {{c2::B12 Deficient Myelopathy}} {{c1::Distal paraesthesia (hands and feet)}} {{c1::Extensor plantars and Areflexia}} {{c1::Degenerati…
Published	02/10/2024	Causes of B12 Deficiency {{c1::Diet (vegans)}} {{c1::Pernicious anaemia (autoimmune condition in which antibodies to intrinsic factor prevent B12 abso…
Published	02/10/2024	Vitamin B12 is absorbed from the gut by a binding protein known as {{c1::intrinsic factor (IF)}} secreted by gastric parietal cells
Published	02/10/2024	Investigation of Spinal Stroke/Infarction{{c1::MRI (showing anterior area of infarction)}}
Published	02/10/2024	Investigations of B12 Deficient Myelopathy{{c1::Low vitamin B12 level}}{{c1::Parietal cell antibodies (if concerned about pernicious anaemia)}}{{c1::B…
Published	02/10/2024	If you are concerned about Pernicious anaemia causing B12 deficient myelopathy, then investigate by {{c1::Parietal cell antibodies}}
Published	02/10/2024	Treatment of Spinal Stroke {{c1::Maintain adequate blood pressure}} {{c1::Antiplatelet therapy with aspirin/clopidogrel}}
Published	02/10/2024	Treatment of B12 Deficient Myelopathy {{c1::Intramuscular Vitamin B12}} {{c1::Folate supplementation (after B12 is given)}} {{c1::Cessation of nitrous…
Published	02/10/2024	Vitamin B12 can be normal with {{c1::nitrous oxide}} usage, in which homocysteine and methylmalonic acid levels are elevated instead
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