Notes in 9. Hemoglobin/Allosterism

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Published 06/03/2024 important characteristics of M-M behavior vs cooperative binding behavior (hemoglobin)
Published 06/03/2024 myoglobin vs hemoglobin kinetics
Published 06/03/2024 cooperativity is measured by the ...
Published 06/03/2024 e95117453c754594b5fc84bdfa3eb3af-ao-1
Published 06/03/2024 e95117453c754594b5fc84bdfa3eb3af-ao-2
Published 06/03/2024 e95117453c754594b5fc84bdfa3eb3af-ao-3
Published 06/03/2024 e95117453c754594b5fc84bdfa3eb3af-ao-4
Published 06/03/2024 e95117453c754594b5fc84bdfa3eb3af-ao-5
Published 06/03/2024 e95117453c754594b5fc84bdfa3eb3af-ao-6
Published 06/03/2024 e95117453c754594b5fc84bdfa3eb3af-ao-7
Published 06/03/2024 e95117453c754594b5fc84bdfa3eb3af-ao-8
Published 06/03/2024 e95117453c754594b5fc84bdfa3eb3af-ao-9
Published 06/03/2024 resting level of O2 consumption
Published 06/03/2024 Explain via the Fick Equation why hypothetical myoglobin-loaded erythrocytes could not reasonably supply the resting level of oxygen consumption (250 …
Published 06/03/2024 difference between myoglobin/hemoglobin structures
Published 06/03/2024 Describe how heme-initiated structural remodeling at the oligmeric interface occurs. (both O2 side and 2,3-BPG side) ALLOSTERIC REGULATION
Published 06/03/2024 Describe how hemoglobin's inter-subunit salt-bridges are affected by the conformational transition from T-state to R-state.
Published 06/03/2024 describe the 'stickiness' of hemoglobin as it relates to O2 saturation (I am making up this term. Not Dr. King's)
Published 06/03/2024 which state of hemoglobin is more favored (T/R)
Published 06/03/2024 mechanism by which 2,3-BPG regulate hemoglobin
Published 06/03/2024 describe the mechanism by which increased pH stabilizes T-state hemoglobin
Published 06/03/2024 Describe the mechanism by which CO2 stabilizes T-state hemoglobin and why this is desirable/important.
Published 06/03/2024 Define the Bohr Effect
Published 06/03/2024 Define the Haldane Effect:
Published 06/03/2024 Describe the key characteristics of thalassemia.
Published 06/03/2024 Describe the key characteristics of sickle cell anemia
Published 06/03/2024 Describe the key characteristics methemoglobinemia.
Published 06/03/2024 Describe the diagnostic uses of hemoglobin in FMRI
Published 06/03/2024 Describe the diagnostic uses of hemoglobin in HbA1c
Published 06/03/2024 Describe the diagnostic uses of hemoglobin in pulse-oximetry
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