Notes in Malaria: Clinical

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Status	Last Update	Fields
Published	01/03/2024	test {{c1::test}}
Published	01/06/2024	Genetic factors affecting malaria infectivityProtective {{c1::TNF alleles Haptoglobin phenotype HH131 genotype }}More severe{{c2::…
Published	01/06/2024	Clinical features of uncomplicated malaria Incubation for minimum {{c1::7}} days symptoms = {{c2::Fever, flu-like, headache, myalgias, …
Published	01/06/2024	Cerebral malaria Seizures and decreased consciousness {{c2::Decorticate}} rigidity = abnormal {{c1::flexion}} {{c2::Decerebrate}}&…
Published	01/06/2024	Renal impairment due to MalariaCreatinine {{c1::high}} Treat with {{c2::hydration and transfusion}}
Published	01/06/2024	Acidosis due to malaria{{c1::Shows as hyperventilation/ kussmaul breathing Negative ionotropism Impaired consciousness Vomiting and abd…
Published	01/06/2024	Hypoglycaemia due to malaria{{c1::Anxiety, sweating, dilated pupils, breathless, tachycardic Can progress to worse consciousness, convulsions, sh…
Published	01/06/2024	Anemia in Malaria is due to:{{c1::Lysis of erythrocytes w parasites and those withoutSequestration of erythrocytes w parasites Sequestration of i…
Published	01/06/2024	Bleeding in MalariaThrombocytopenia due to {{c1::Sequestration and destruction of platelets Platelet consumption as part of DIC}}
Published	01/06/2024	management of malaria in pregnancyNon immune women {{c1::Can have severe complications like hypoglycemia and pulmonary edema Higher mortalit…
Published	01/06/2024	management of malaria in pregnancy Partially immune {{c1::Risk of abortion, still birth, premature deliveryLow birth weight infants Inc…
Published	01/06/2024	management of malaria in pregnancy = {{c1::quininine infusion}}
Published	01/06/2024	diagnosis of malaria can be done in 4 ways:{{c1::clinical parasitological immunological ({{c2::plasmodium LDH, Aldolase and Histidine rich p…
Published	01/06/2024	General malaria management Frequent assessment of {{c1::vital signs }}{{c1::Supportive}} therapy Assess and treat {{c1::…
Published	01/06/2024	Pharmacological treatment of malaria Severe malaria {{c1::IV artesunate Pts with >2% parasitaemia Switch to PO artemisinin comb…
Published	01/06/2024	pharmacological treatment of malaria Uncomplicated malaria P falciparum {{c1::Artemisinin combination therapy (ACT)}}P ovale, vivax and…
Published	01/06/2024	pharmacological treatment of malaria Pregnant women {{c1::Chloroquine (+ clindamycin in P falciparum)}}
Published	01/06/2024	adverse effects of quinine {{c1::Cinchonism on day 2-3Hypoglycemia Optic atrophy }}
Status	Last Update	Fields