Notes in Foundational Science

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Published	08/28/2024	Cells that are constantly dividing throughout their life span are known as {{c1:: Labile cells aka stem cells.}} Some examples are {{c2::skin cel…
Published	08/28/2024	Cells that enter the cell cycle "only when they need to" are known as{{c1:: Stable cells aka quiescent cells}}. Examples are {{c2:: liver and kid…
Published	08/28/2024	Cells that do NOT and will NOT enter the cell cycle to regenerate are known as{{c1:: Permanent cells}}. These type of cells are found in {{c2:: t…
Published	08/28/2024	After neutrophills have "neutralized" the wound site by making sure it was free of infection, {{c1:: macrophages}} recruit other cells via citoki…
Published	08/28/2024	Macrophages recruit three cell types. Which are: {{c1:: Myofibroblasts, Angioblasts, Fibroblasts}}
Published	08/28/2024	What do myofibroblasts do when they arrive to the wound site?{{c1:: Since they have both smooth muscle abilities and fibroblast abilities, they induce…
Published	08/28/2024	What do Angioblasts do when they arrive to the wound site?{{c1:: As the collagen its being laid down by myofibroblasts and fibroblasts, the cells need…
Published	08/28/2024	During angiogenesis, immature collagen {{c1::type III}} fibers matture to collagen  {{c2::type I}} fibers. The latter type is the one u…
Published	08/28/2024	What do Fibroblasts do in wound healing?{{c1:: It produces most of the extracellular matrix, including fibronectin and collagen (type III aka immature…
Published	08/28/2024	What is the function of fibronectin?{{c1:: Provides tensile strength to the connective tissue matrix and "glues" other substances and cells together.}…
Published	08/28/2024	The final collagenous(type III) structure is called a {{c1:: scar}}
Published	08/28/2024	Healing by first intention refers to{{c1:: the process of healing that results from a surgical incision and ends with a complete return to function, a…
Published	08/28/2024	What is secondary intention healing ?{{c1:: It's the wound healing process that comes from large wounds and/or deep, unclean wounds. }}
Published	08/28/2024	What are some features of secondary intention healing?{{c1:: * Wound contraction can't be done by myofibroblasts so the granulation tissue stays expos…
Published	08/28/2024	What does delayed wound healing mean?{{c1:: it refers to local or system influences which complicates and delayes the healing process}}
Published	08/28/2024	List the factors that primarily determine wound healing{{c1::  1. Site of the wound2. Infection 3. Mechanical factors4. Age5. Circulatory status6…
Published	08/28/2024	How does mechanical factors influence delayed wound healing? {{c1:: Because wounds heal faster if the margins (of the injured tissue) are nearly …
Published	08/28/2024	Wounds involving ischemic tissues heal {{c1::poorly}}
Published	08/28/2024	Diabetes is a disease maker by chronic {{c1:: ischemia}} and poor wound healing.
Published	08/28/2024	General well-being {{c1::promotes}} wound healing.
Published	08/28/2024	What vitamin is essential for wound healing? {{c1:: vitamin C}}
Published	08/28/2024	What does dehiscence mean?{{c1:: Separation of wound margins.}}
Published	08/28/2024	What are the two complications of wound healing as presented in the lecture?{{c1::  1. Deficient Scar formation2. Excess scar formation}}
Published	08/28/2024	What causes deficient scar formation?{{c1:: It is caused by sluggish formation of granulation tissue (seen in diabetic patients) and/or inadequate col…
Published	08/28/2024	Excess scar formation leads to {{c1::Keloid}} formation
Published	08/28/2024	What are Keloids?{{c1:: Hypertrophic scars that are mainly made of type III collagen (immature collagen) and come from defective remodeling of scar ti…
Published	08/28/2024	True or False: Keloid formation is only seen in second intention healing{{c1:: False. Keloid formation is seen in both first and second intention heal…
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