Notes in 24 Rabies, Slow Virus Infections, & Prion Diseases

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Published 07/30/2024 At an autopsy the brain shows widespread neuronal degeneration, a spongy appearance due to many vacuoles between the cells, no inflammation, and no ev…
Published 07/30/2024 At an autopsy the brain shows widespread neuronal degeneration, a spongy appearance due to many vacuoles between the cells, no inflammation, and no ev…
Published 07/30/2024 {{c1::Kuru:: Specific Transmissible Spongiform Encephalopathy}} occurred only in the eastern highlands of New Guinea and was spread by customs surroun…
Published 07/30/2024 {{c1::Creutzfeldt-Jakob Disease:: Specific Transmissible Spongiform Encephalopathy}} develops gradually, with progressive dementia, ataxia, and myoclo…
Published 07/30/2024 {{c1::Iatrogenic/ Acquired CJD::Type of Creutzfeldt-Jakob Disease}} has been transmitted accidentally by contaminated growth hormone preparations from…
Published 07/30/2024 {{c1::Sporadic CJD::Type of Creutzfeldt-Jakob Disease}} is caused by the spontaneous transformation of normal prion protein into abnormal prions
Published 07/30/2024 {{c1::Progressive multifocal leukoencephalopathy::Disease}} is a rare, usually fatal, demyelinating CNS disease caused by {{c2::polyomavirus JC virus:…
Published 07/30/2024 {{c1::Subacute Sclerosing Panencephalitis::Disease}} is caused by the persistence of {{c2::measles virus::etiologic agent}} infection with s…
Published 07/30/2024 What medically important virus has a rod or bullet shaped morphology with protruding glycoprotein spikes?{{c1:: Rabies Virus}}
Published 07/30/2024 Rabies Survives storage at {{c1::4°C::Temp}} for weeks and at {{c1::-70°C::Temp}} for years and isinactivated by {{c2::CO2}}
Published 07/30/2024 Rabies is Rapidly killed by: {{c1::Exposure to UV radiation Sunlight Heat (1 hour at 50 °C) Lipid solvents (ether and 0.1% sodium deoxychola…
Published 07/30/2024 Rabies virus does NOT need to be transcribed before translation {{c1::False::(T/F)}}
Published 07/30/2024 Rabies infects insects{{c1::False::(T/F)}}
Published 07/30/2024 QC: Longer and Variable Incubation PeriodStreet VirusFixed VirusAnswer: {{c1::A}}
Published 07/30/2024 QC: Regularly produce intracytoplasmic inclusion bodiesStreet VirusFixed VirusAnswer: {{c1::A}}
Published 07/30/2024 QC: Inclusion bodies are found only with difficulty Street VirusFixed VirusAnswer: {{c1::B}}
Published 07/30/2024 QC: No longer multiplies in extraneural tissuesStreet VirusFixed VirusAnswer: {{c1::B}}
Published 07/30/2024 Substitution of amino acid position {{c1::333::number}} of the G glycoprotein in rabies results in loss of virulence 
Published 07/30/2024 Rabies has only 1 serotype {{c1::True::(T/F)}}
Published 07/30/2024 Rabies MOT: {{c1::by bites of rabid animals or by contact with saliva from rabid animal }}Other routes of infection:{{c1::Inhalation of aerosoliz…
Published 07/30/2024 VR:Younger AgeSusceptibility to RabiesAnswer: {{c1::A}}
Published 07/30/2024 VR:Shallow BiteIncubation Time of RabiesAnswer: {{c1::A}}
Published 07/30/2024 VR:Bite to Face or Head AreaIncubation Time of RabiesAnswer: {{c1::B}}
Published 07/30/2024 VR:Bite to LegsMortality from RabiesAnswer: {{c1::B}}
Published 07/30/2024 This phase in the course of rabies infection and syndrome takes the longest time:{{c1::Incubation Period }}
Published 07/30/2024 What stage in the course of rabies infection is the patient in if the patient presents with nervousness, bizarre behavior, increased salivation a…
Published 07/30/2024 {{c1::Cardiorespiratory arrest}} is the major cause of death in rabies
Published 07/30/2024 {{c1::Negri Body}} is a histopathologic finding found in the brain and spinal cord and is pathognomonic for rabies.
Published 07/30/2024 Most Rapid and accurate way to diagnose Rabies? {{c1::Rabies Antigen detection using immunofluorescence or immunoperoxidase staining}}
Published 07/30/2024 Rabies antibodies in CSF are only detectable if the patient is infected with rabies.{{c1::True::(T/F)}}
Published 07/30/2024 All animals considered “rabid or suspected rabid” should be sacrificed immediately for laboratory examination of neural tissues {{c1::True::(T/F)…
Published 07/30/2024 Most effective management for a symptomatic patient infected with rabies?{{c1::Final goodbyes or/and prayers char none cuz almost 100% patient go…
Published 07/30/2024 Pre-Exposure prophylaxis is indicated for {{c1::Persons at high risk of contact with rabies virus Research and diagnostic laboratory workers…
Published 07/30/2024 A relative visited a patient with signs and symptoms of rabies.{{c1::1, No PEP::Category, Post-Exposure Prophylaxis}}
Published 07/30/2024 Touching and Feeding rabid animals{{c1::1, No PEP::Category, Post-Exposure Prophylaxis}}
Published 07/30/2024 Patient was bitten by unprovoked stray dog {{c1::3, Vaccine + RIG::Category, Post-Exposure Prophylaxis}}
Published 07/30/2024 Patient had Minor abrasions without bleeding while handling animals{{c1::2, Vaccine Only::Category, Post-Exposure Prophylaxis}}
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