Notes in physio

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Published	11/05/2024	negative side effect of excessive RBC numbers
Published	11/05/2024	{{c1::tissue oxygenation}} is the most important regulator of erythropoiesis
Published	11/05/2024	hypoxia stimulates erythropoiesis by increasing {{c1::erythropoietin}} hormone secretion
Published	11/05/2024	erythropoietin is chemically a {{c1::glycoprotein}}
Published	11/05/2024	{{c2::85-90}}% of erythropoietin come from the {{c1::kidney}} (organ) and {{c2::10-15%}} from the {{c1::liver}}
Published	11/05/2024	half-life of erythropoietin
Published	11/05/2024	mechanisms by which erythropoietin increases hematopoisis
Published	11/05/2024	factors affecting erythropoietin secretion
Published	11/05/2024	mechanism by which hypoxia increases erythropoietin
Published	11/05/2024	HIF1 is stimulated by {{c1::cobalt salts}} (substance)
Published	11/05/2024	hormones that increase erythropoietin secretion
Published	11/05/2024	anemia associated with renal failure can only be treated by {{c1::erythropoietin}}
Published	11/05/2024	in aplastic anemia stem cells do not respond to {{c1::erythropoietin}} hormone
Published	11/05/2024	requirements for erythropoiesis
Published	11/05/2024	dietary substances needed for erythropoiesis
Published	11/05/2024	importance of copper and cobalt in hemoglobin
Published	11/05/2024	vitamin B12 and folic acid are called {{c1::maturation factors}} (erythropoiesis requirement)
Published	11/05/2024	importance of vitamin B12 and folic acid in erythropoiesis
Published	11/05/2024	vitamin B12 and folic acid deficiency results in {{c1::megaloblastic}} or {{c1::macrocytic}} anemia
Published	11/05/2024	{{c1::estrogen}} hormone inhibits erythrpoiesis
Published	11/05/2024	importance of liver in erythropoiesis
Published	11/05/2024	{{c1::reticulo-endothelial system}} cells break down old RBCs
Published	11/05/2024	heamoglobin is broken down to {{c1::heme}} and {{c1::globin}}
Published	11/05/2024	heme is broken down into {{c1::bile pigments (biliverdin and bilirubin)}} and {{c1::iron}}
Published	11/05/2024	{{c1::committed stem cells}} (pluripotent stem cells, multipotent stem cells, progenitor cells) cells are stimulated to produce proerythroblast by ery…
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