Notes in III. Nitroglycerin

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Published 10/21/2024 a powerful vasodilator used for CAD patients 
Published 10/21/2024 {{c2::Nitroglycerin}}works by {{c1::dilating or widening}} blood vessels, an action which {{c1::reduces}} the workload on the heart, as it become…
Published 10/21/2024 {{c1::Glutathione-S-Transferase}} is an enzyme that metabolizes Nitroglycerin, converting it into {{c2::Nitric Oxide (NO)}}
Published 10/21/2024 {{c1::Nitroglycerin}}: MOA at the Cellular Level {{c2::Nitric Oxide Production }}{{c3::Activation of Guanylate Cyclase}}{{c4::Smooth Muscle …
Published 10/21/2024 Nitroglycerin: MOA at the Cellular Level (4)
Published 10/21/2024 Nitroglycerin: MOA at the Cellular Level: STEPS 1-4
Published 10/21/2024 Nitroglycerin: MOA at the Cellular Level: STEPSStep 1: {{c1::Nitroglycerin Enters the Cell}}Step 2: {{c2::Nitric Oxide Production}}Step 3: {{c3::Vasod…
Published 10/21/2024 Nitroglycerin: MOA  Nitric Oxide (NO) Production → Nitroglycerin is metabolized by the enzyme {{c1::Glutathione-S-Transferase}} which convert…
Published 10/21/2024 Nitroglycerin: MOA {{c3::Activation of Guanylate Cyclase}} → The produced {{c1::Nitric Oxide (NO)}} activates the enzyme {{c2::Guanylate Cyc…
Published 10/21/2024 Nitroglycerin: MOA {{c1::Smooth Muscle Relaxation}} Increased levels of {{c2::Cyclic Guanosine Monophosphate (cGMP)}} in the smooth muscle c…
Published 10/21/2024 Nitroglycerin: MOA at Cellular Level Step 1: Nitroglycerin Enters the Cella. Nitroglycerin Enters the {{c2::Vascular Smooth Muscle cell}}Nitrogly…
Published 10/21/2024 Nitroglycerin: MOA at Cellular Level Step {{c1::2: Nitric Oxide Production}}● {{c1::Nitric Oxide (NO) production}} > {{c2::Guanylyl C…
Published 10/21/2024 Nitroglycerin: MOA at Cellular Level Step {{c1::3: Vasodilation}}{{c2::a. Increased cGMP levels }}{{c3::b. Relaxation of Vascular Sm…
Published 10/21/2024 Nitroglycerin: MOA at Cellular Level Step 3: Vasodilation (a-d)?
Published 10/21/2024 Nitroglycerin: MOA at Cellular Level Step 3: Vasodilation{{c1::b. Relaxation of Vascular Smooth Muscle}}→ Elevated {{c2::cGMP}} levels …
Published 10/21/2024 Nitroglycerin: MOA at Cellular Level Step 3: Vasodilation {{c1:: c. Increased Blood Flow}}→ The {{c2::vasodilation}} of the blood vesse…
Published 10/21/2024 Nitroglycerin: MOA at Cellular Level Step 3: Vasodilation {{c1:: d. Mechanism of Nitroglycerin }} → Nitroglycerin is metab…
Published 10/21/2024 Nitroglycerin: MOA at Cellular Level Step 4: {{c1::Reduced Workload on the Heart}}{{c2::Reduction in Myocardial Oxygen Demand}}{{c3::Decreas…
Published 10/21/2024 Nitroglycerin: MOA at Cellular Level Step 4: Reduced Workload on the Heart
Published 10/21/2024 Other drugs that can be given aside from nitroglycerin are {{c1::beta blockers}}; it prevents death in px with coronary artery disease 
Published 10/21/2024 Nitroglycerin: MOA {{c1::Guanylate Cyclase}}▪ Catalyzes the conversion of {{c2::Guanosine Triphosphate (GTP)}} to {{c2::Cyclic Guanosine Monophos…
Published 10/21/2024 {{c1::angina pectoris}} is a condition characterized by chest pain or discomfort due to reduced blood flow to the heart 
Published 10/21/2024 Nitroglycerin: MOA at Cellular Level Step 1: Nitroglycerin Enters the Cell{{c1::b. Enzymatic Conversion to Nitric Oxide (NO)}}→ Inside …
Published 10/21/2024 {{c2::Nitroglycerin}} is commonly prescribed to patients with {{c1::angina pectoris}}
Published 10/21/2024 Nitroglycerin: MOA {{c3::Nitric Oxide (NO) Production}} → Nitroglycerin is metabolized by the enzyme {{c1::Glutathione-S-Transferase}} which…
Published 10/21/2024 Nitroglycerin: MOA {{c1::Reduced Afterload}} {{c2::Vasodilation}} caused by the relaxation of smooth muscle in blood vessels leads to a {{c1…
Published 10/21/2024 Nitroglycerin: MOA at Cellular Level Step 1: Nitroglycerin Enters the Cella. {{c1::Nitroglycerin Enters the Vascular Smooth Muscle cell}}b. {{c1:…
Published 10/21/2024 Nitroglycerin: MOA at Cellular Level Step 1: Nitroglycerin Enters the Cell{{c1:: b. Enzymatic Conversion to Nitric Oxide (NO) }}→ Insid…
Published 10/21/2024 Nitroglycerin: MOA at Cellular Level Step 3: Vasodilation {{c1::a. Increased cGMP levels}}→ {{c2::Nitric oxide (NO)}} stimulates the en…
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