Notes in f. Introduction to Enzymes

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Published	07/28/2024	{{c1::Cobalamin}} is a coenzyme that mediates {{c2::alkylation}} reactions
Published	07/28/2024	{{c1::Folic acid}} is a precursor to the coenzyme {{c2::Tetrahydrofolate}}
Published	07/28/2024	{{c1::Folic acid (and Vitamin B12)}} deficiencies lead to {{c2::anemia}}
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Published	07/28/2024	Phenylalanine hydroxylase is an example of a(n) {{c1::oxidoreductase}}
Published	07/28/2024	What reaction is catalyzed by phenylalanine hydroxylase? What cofactor and conezyme are needed? What kind of reaction is it?
Published	07/28/2024	What cofactors are utilized by phenylalanine hydroxylase?
Published	07/28/2024	Elevated phenylalanine levels along with an increased phenylalanine-tyrosine ratio is indicative of an error in the enzyme {{c1::phenylalanine hy…
Published	07/28/2024	{{c1::Phenylketonuria}} is the disease associated with errors in the enzyme {{c2::phenylalanine hydroxylase}}
Published	07/28/2024	What other reagent (excluding cofactors (tetrahydrobiopterin and Fe (II) and phenylalanine) is necessary for the reaction catalyzed by phenylalanine h…
Published	07/28/2024	What is the function of Carnitine palmitoyl transferase I and what kind of enzyme is it?
Published	07/28/2024	Carnitine palmitoyl transferase I is an example of a {{c1::transferase}}
Published	07/28/2024	An increased ratio of free carnitine to C16:0 and C18:0 acylcarnitines is indicitive of a metabolic error in {{c1::carnitine palmitoyl transferas…
Published	07/28/2024	{{c1::Carnitine palmitoyl transferase deficiency type I}} is a disease associated with errors of the enzyme {{c2::carnitine palmitoyl transferase…
Published	07/28/2024	Arginase is an example of a {{c1::hydrolase}} enzyme
Published	07/28/2024	What is the function of Arginase and what kind of enzyme is it?
Published	07/28/2024	Arginine levels elevated to 5- to 10-fold, with other amino acids in the normal range is indicitive of errors in {{c1::arginase}} enzymes
Published	07/28/2024	{{c1::Arginemia}} is a disease associated with metabolic errors of the enzyme {{c2::arginase because arginase removes the nitrogen from Argi…
Published	07/28/2024	Cystathionine Beta Synthase is an example of a {{c1::lyase}}
Published	07/28/2024	What is the function of Cystathionine Beta Synthase? And what kind of enzyme is it?
Published	07/28/2024	The cofactor necessary for cystathionine beta synthase activity is {{c1::PLP (B6 derivative) because pyridoxal phosphate (PLP) is what is orginal…
Published	07/28/2024	Elevated levels of methionines prompt plasma testing for elevated homocysteine as a result of metabolic errors of the enzyme {{c1::cystathionine …
Published	07/28/2024	{{c1::Homocystinuria}} is a disease indicative of metabolic errors of the enzyme {{c2::cystathionine beta synthase}}
Published	07/28/2024	Methylmalonyl-CoA mutase is an example of a {{c1::isomerase}}
Published	07/28/2024	What is the function of methylmalonyl-CoA mutase and what kind of enzyme is it?
Published	07/28/2024	{{c1::Methylmalonic acidemia}} is a disease that results from metabolic errors in the enzyme {{c2::methylmalonyl-CoA mutase}}
Published	07/28/2024	Methylmalonyl-CoA mutase requires the cofactor {{c1::Cobalamin (vitamin B12) (5-deoxyadenosylcobalamin (AdoCbl) to be specific}}
Published	07/28/2024	Arginosuccinate synthetase is an example of a {{c1::Ligase}}
Published	07/28/2024	What kind of enzyme is arginosuccinate synthetase and what is its function?
Published	07/28/2024	When up to 100 times the normal level of citrulline is present, a metabolic error may be occuring in {{c1::arginosuccinate synthetase}} because {…
Published	07/28/2024	{{c1::Citrullinemia}} is a disease resulting from metabolic errrors in the enzyme {{c2::arginosuccinate synthetase}}
Published	07/28/2024	The 4 catalytic mechanisms employed by enzymes are?
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Published	07/28/2024	In moderate injuries, {{c1::Alanine aminotransferase}} is elevated.In severe damages, {{c1::Aspartate aminotransferase}} is elevated
Published	07/28/2024	What are 3 ways metals can contribute to catalysis?
Published	07/28/2024	superoxide dismutase (SOD1) has cofactors {{c1::Cu}} and {{c1::Zn}} that neutralizes {{c1::superoxides}} . Mutations in SOD (Ala4Val and Gly93Al…
Published	07/28/2024	Carbonic anhydrase uses {{c1::Zn}} to generate {{c1::OH-}} and to ultimately create {{c1::bicarbonate}}
Published	07/28/2024	What is the treatment for phenylketonuria
Published	07/28/2024	What is the treatment for carnitine palimtoyl transferase deficiency type 1
Published	07/28/2024	What is the treatment for arginemia
Published	07/28/2024	What is the treatment for homocystinuria
Published	07/28/2024	What is the treatment for Methyl Malonic Acidemia?
Published	07/28/2024	What is the treatment for citrullinemia?
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