Notes in Physical Biochem Exam 2::Lecture 1

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Status	Last Update	Fields
Published	10/14/2024	{{c1::Xray diffractometry, crystallography, XRC:}}• The {{c2::oldest}} of the methods• Continues to contribute the most depositions• Can do *{{c2::Som…
Published	10/14/2024	{{c1::Nuclear magnetic resonance spectroscopy, NMR:}}• {{c2::Small to medium}}-sized structures (size-to-difficulty: {{c2::exponential}})• Fantastic a…
Published	10/14/2024	{{c1::Cryo-electron microscopy, CEM:}}• {{c2::medium to huge}} structures (size-to-difficulty: {{c2::linear}})• Not good for {{c2::dynamics}}• Not dep…
Published	10/14/2024	{{c1::Computational (QM & MM):}}• {{c2::Small to medium-large}}-sized structures (size-to-difficulty: {{c2::exponential}})• Can calculate {{c2::dy…
Published	10/14/2024	Structure size keysmall: {{c1::0-200 AA}}medium: {{c1::200-1,000 AA}}large: {{c1::1,000+ AA}}
Published	10/14/2024	XRC diffraction spots are in {{c1::reciprocal space}}
Published	10/14/2024	XRC diffraction spots are the result of {{c1::complex wave interactions}} from all atoms in the crystal
Published	10/14/2024	{{c1::macromolecules}} in a {{c1::crystal lattice}} are far more complex than a sphere of mirrors
Published	10/14/2024	Macromoleulces have light "reflecting" planes of matter called {{c1::Bragg planes}}
Published	10/14/2024	The spots from {{c1::crystal matter planes}} can be used to back calculate {{c2::electron density}} that causes the spots
Published	10/14/2024	If we know {{c2::electro density}}, we have the {{c1::structural model }}
New Card	10/14/2024	hi {{c1::timing-leopard-india-pennsylvania-oregon-virginia}}
Status	Last Update	Fields