Notes in o. Liver: Xenobiotic Metabolism

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Status	Last Update	Fields
Published	06/08/2024	what is the major reaction carried out by CYP (Cytochrome P450 superfamily) enzymes?
Published	06/08/2024	where are Cytochrome P450 (CYP) located?
Published	06/08/2024	why is hydroxylation of xenobiotics significant
Published	06/08/2024	clinical significance of CYP3A4
Published	06/08/2024	clinical significance of CYP2D6
Published	06/08/2024	CYP3A4what do the CYP, the 3, the A and the 4 signify
Published	06/08/2024	Phase 1 vs Phase 2 vs Phase 3 xenobiotic metabolism
Published	06/08/2024	Phase 2 conjugates are transported into urine/plasma via ... proteins
Published	06/08/2024	what are the three different enzymes that metabolize alcohol in the liver, and what is the common final product of all of them
Published	06/08/2024	what are two harmful byproducts of CYP2E1 metabolism of alcohol?
Published	06/08/2024	how does NADH cause fatty liver?
Published	06/08/2024	how does acetaldehyde cause fatty liver?
Published	06/08/2024	how does alcohol metabolism by ADH produce inflammation?
Published	06/08/2024	describe how glutathione destroys ROS
Published	06/08/2024	note: local anesthetic metabolism can result in oxidation of hemoglobin to methemoglobin
Published	06/08/2024	what are 'xenobiotics'
Published	06/12/2024	describe first pass effect.
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