Notes in LE20 Intro to Hematology

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Published	10/07/2024	Plasma makes up {{c1::55}}% of total blood, comprised of (x5) {{c2::water, proteins, electrolytes, small molecules, hormones}}.Plasma is {{c3::anticoa…
Published	10/07/2024	Plasma Proteins{{c1::Albumin}}most abundant protein in plasmamaintains oncotic pressurebinds hormones, fatty acids, medications{{c2::Transport protein…
Published	10/07/2024	Red blood cell functiontransports {{c1::oxygen}} to tissues and {{c2::CO2}} from tissuescomprised of {{c3::hemoglobin}} protein
Published	10/07/2024	Properties of biconcave disc shape of RBCmaximuze {{c1::cell surface area}} for oxygen exchangemore {{c2::flexible}} membrane allowing RBC to travel t…
Published	10/07/2024	{{c1::Spherocytes}} are red blood cells that are round like a sphere, lack {{c3::central pallor}} VS normal RBCs that are {{c2::disk-shaped}}. Th…
Published	10/07/2024	Hemoglobin structure:{{c4::heme}}2 {{c3::alpha}} + 2 {{c2::beta}} subunits -> tetramer protein protoporphyrin molecule contains {{c1::Fe2+ tha…
Published	10/07/2024	Binding affinity of oxygen is mediated by shifting of hemoglobin states:{{c4::T}} state has {{c1::low}} affinity for oxygen binding to hemoglobin{{c3:…
Published	10/07/2024	Hemoglobin-Oxygen dissociation curveLeftward shift of curve:{{c1::increased}} oxygen affinity{{c2::decreased}} oxygen delivery in the lungsrightward s…
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