Notes in k. Translation

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Published	07/28/2024	Ribosomal RNA (80% of total RNA) precursors 28S, 18S, and 5.8S are transcribed by RNA Polymerase {{c1::I}}
Published	07/28/2024	tRNA (10% of RNA) is transcribed by RNA polymerase {{c1::III}}
Published	07/28/2024	5S rRNA is transcribed by RNA polymerase {{c1::III}}
Published	07/28/2024	rRNA genes are found in tandem arrays and are clustered at specific sites on 5 chromosomes called {{c1::nuclear organizer regions (NORS)}}
Published	07/28/2024	rRNA's undergo what 2 chemical modification in the nucleolus?
Published	07/28/2024	Modifications in 45S rRNA (which is a precursor to 18s, 5.8s, and 28s rRNA) is brought about by {{c1::small nuceolar RNAs (snoRNAs)}} that work a…
Published	07/28/2024	The 2 subunits of the ribosome are the?
Published	07/28/2024	The 60s subunit (which matures from the large ribonucleo-protein particle in the nucleolus) is made of which rRNAs?
Published	07/28/2024	The 40s subunit is made of which rRNAs?
Published	07/28/2024	Initiation is started by the {{c1::tRNAiMet}} binding to the small subunit of ribosome in cytosol because the {{c1::tRNA initator Met}} has a specific…
Published	07/28/2024	{{c1::IRES (Internal ribosome entry sites)}} are sequences that allow for protein translation to begin in the middle of an mRNA, mostly viral transcri…
Published	07/28/2024	A {{c1::polyribosome}} is a cluster of ribosomes bound to a single mRNA
Published	07/28/2024	Tetracylin is an antibiotic that blocks {{c1::bacterial}} translation
Published	07/28/2024	Streptomycin is an antibiotic that blocks {{c1::bacterial}} translation
Published	07/28/2024	Chloramphenicol is an antibiotic that blocks {{c1::bacterial}} translation
Published	07/28/2024	Erythromycin is an antibiotic that blocks {{c1::bacterial}} translation
Published	07/28/2024	Cycloheximide is an antibiotic that blocks {{c1::eukaryotic}} translation
Published	07/28/2024	Anisomycin is an antibiotic that blocks {{c1::eukaryotic}} translation
Published	07/28/2024	the {{c1::5' UTR}} sequence of mRNA has cis-elements that bind translational repressor proteins
Published	07/28/2024	The {{c1::3' UTR}} sequence of mRNA may contain miRNA binding sites (which can cause degradation or translational supression) and cis-elements fo…
Published	07/28/2024	43bd2c1891e745b0bffd1676e3f0a7fb-ao-1
Published	07/28/2024	43bd2c1891e745b0bffd1676e3f0a7fb-ao-2
Published	07/28/2024	43bd2c1891e745b0bffd1676e3f0a7fb-ao-3
Published	07/28/2024	43bd2c1891e745b0bffd1676e3f0a7fb-ao-4
Published	07/28/2024	NMD stands for {{c1::nonsense-mediated decay}}
Published	07/28/2024	At the end of a successful splice event an {{c1::exon junction complex (EJC)}} protein remains as a marker
Published	07/28/2024	NMD (nonsense-mediated decay) is triggered by?
Published	07/28/2024	How does NMD play a role in the pathology of Duchenne Muscular Dystrophy?
Published	07/28/2024	Transcription of 45S rRNA occurs in the {{c1::nucleolus}} and large ribosomal subunits are assembled there
Published	07/28/2024	The Ribosome is a {{c1::ribozyme (2/3 RNA & 1/3 Protein)}} where rRNA forms the core surrounded by protein
Published	07/28/2024	tRNA {{c1::anti-codon loop}} matches with the mRNA sequence that is being translated
Published	07/28/2024	61 possible codons are recognized from {{c1::51 tRNA genes}} because of {{c2::the 3' wobble codon}}
Published	07/28/2024	Described how tRNAs are charged with specific amino acids
Published	07/28/2024	Translation is terminated by {{c1::binding of release factor, which recognizes stop codons, to the A site}} which signals to the P site that it is tim…
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