Notes in ✧ Cell Cycle

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Published 01/14/2024 Which cell cycle checkpoint is blocked by p53?{{c1::G1 to S}}
Published 01/14/2024 Which cell cycle checkpoint is blocked by hypophosphorylated Rb?{{c1::G1 to S}}
Published 01/14/2024 In {{c1::mitosis::cell cycle phase}}, DNA condenses to form chromosomes
Published 01/14/2024 What cell cycle phase do DNA and histone synthesis occur?{{c1::S phase}}
Published 01/14/2024 What is the shortest phase of the cell cycle?{{c1::M phase (mitosis + cytokinesis)}}
Published 01/14/2024 Which cell cycle phase is characterized by resting, non-dividing cells?{{c1::G0}}
Published 01/14/2024 What cell type remains in G0 and can only regenerate from stem cells?{{c1::Permanent}}
Published 01/14/2024 What type of cells are the following examples? {{c1::Permanent::Labile, Stable, or Permanent?}}
Published 01/14/2024 What cell type enters G1 from G0 when stimulated?{{c1::Stable (quiescent)}}
Published 01/14/2024 What type of cells are the following examples? {{c1::Stable (Quiescent)::Labile, Stable, or Permanent?}}
Published 01/14/2024 What cell type never enters G0 and divides rapidly with a short G1?{{c1::Labile}}
Published 01/14/2024 What cell type is affected most by chemotherapy?{{c1::Labile (gut epithelium, skin, hair follicles, etc)}}
Published 01/14/2024 Which cell cycle phase is characterized by DNA synthesis and replication?{{c1::S}}
Published 01/14/2024 Which cell cycle phase(s) are part of interphase? {{c1::G1, S, G2}}
Published 01/14/2024 Which cell cycle phase(s) are NOT part of interphase? {{c1::M}}
Published 01/14/2024 Transcription occurs throughout which cell cycle phases?{{c1::Interphase (G1, S, G2)}}
Published 01/14/2024 Which tumor suppressor protein acts at the G1 check point?{{c1::p53}}
Published 01/14/2024 What type of cell (permanent, labile, stable) are neurons? {{c1::Permanent (do not divide in adulthood)}}
Published 01/14/2024 What type of tissue is comprised of stem cells that can continuously cycle to regenerate tissue? {{c1::Labile}}
Published 01/14/2024 A general rule of chemotherapeutic side effects is that they will affect all {{c1::rapidly}} dividing cells
Published 01/14/2024 Growth Factors induce cellular {{c1::growth}}vs mitogen
Published 01/14/2024 The Cell Cycle is regulated by Cyclins and Cyclin-Dependent Kinases (CDKs) which when {{c2::complexed}} allow cells to bypass {{c1::restriction p…
Published 01/14/2024 The G1 restriction point of the cell cycle is regulated by the tumor suppressors {{c1::p53}} and {{c1::Rb}}
Published 01/14/2024 p53 restricts the cell cycle to G1 by engendering the inhibition of {{c2::CDK4}}, maintaining the {{c1::hypo}}phosphorylated state of Rb
Published 01/14/2024 In response to DNA damage, p53 initially attempts to {{c1::halt}} the cell cycle and facilitates the activity of {{c2::DNA repair}} enzymes*bonus-what…
Published 01/14/2024 If DNA repair is not possible, p53 induces {{c1::apoptosis}}
Published 01/14/2024 Growth Factors stimulate G1 phase by increasing the levels of the {{c1::Cyclins}}
Published 01/14/2024 Once levels of Cyclins reach an appropriate level, these complex with {{c1::Cyclin-Dependent Kinases}} to hyperphosphorylate Rb
Published 01/14/2024 Tumor suppressor genes {{c1::regulate}} cell growth
Published 01/14/2024 Li-Fraumeni syndrome is characterized by multiple malignancies at a(n) {{c1::early}} age
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