Notes in CEP I (Cell communication)

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Published	11/11/2024	9fb3953526ba450381f6a06e6cb7d78c-ao-1
Published	11/11/2024	9fb3953526ba450381f6a06e6cb7d78c-ao-2
Published	11/11/2024	9fb3953526ba450381f6a06e6cb7d78c-ao-3
Published	11/11/2024	1afde28e2efb401c9d7e3f1f2d93e3b0-ao-1
Published	11/11/2024	1afde28e2efb401c9d7e3f1f2d93e3b0-ao-2
Published	11/11/2024	1afde28e2efb401c9d7e3f1f2d93e3b0-ao-3
Published	11/11/2024	1afde28e2efb401c9d7e3f1f2d93e3b0-ao-4
Published	11/11/2024	In {{c2::autocrine signaling}}, the hormone is secreted and the target site is located on the {{c1::secretory cell}} .
Published	11/11/2024	In {{c1::paracrine signaling}}, the hormone is secreted by the secretory cell and targets {{c2::adjacent cells}} due to the {{c2::limi…
Published	11/11/2024	{{c1::Synaptic signaling}} is a type of {{c2::paracrine}} signaling that occurs at a junction between {{c3::two neurons}} using a {{c3::neurotransmitt…
Published	11/11/2024	In {{c1::endocrine signaling}}, a secretory cell releases a hormone directly into {{c1::the blood supply}} to travel to a target cell.
Published	11/11/2024	Before Loewi's experiments, it was unclear whether signaling across the synapse was {{c1::bioelectrical}} or {{c1::chemical}}.
Published	11/11/2024	In 1921, Loewi's experiment involved dissecting two {{c2::beating hearts}} from {{c2::frogs}}, one with the {{c1::vagus nerve}} attached.
Published	11/11/2024	Loewi slowed the first heart by {{c1::electrically stimulating}} the {{c1::vagus nerve}} and then transferred the liquid to the second heart, which {{…
Published	11/11/2024	Loewi's experiment proved that a {{c1::soluble chemical}} released by the {{c2::vagus nerve}} controlled heart rate, which he called {{c3::Vagusstoff}…
Published	11/11/2024	{{c1::Agonists}} are {{c2::compounds that produce the same effects as the neurotransmitter}}.
Published	11/11/2024	Generally, {{c1::Antagonists}} fit into the {{c2::receptor}} but have no {{c2:: response}}, therfore blocking {{c2:: the effects of the native ne…
Published	11/11/2024	{{c3::Nicotine}} is an {{c2::agonist}} that binds to and activates {{c2::nAChRs}} ion channels at the NMJ, causing Na+ influx and resulting in {{c1::m…
Published	11/11/2024	{{c1::Curare}} acts as an {{c2::antagonist}} at the NMJ by binding to {{c3::nAChRs}} and blocking the effect of {{c3::ACh}}, leading to {{c4::skeletal…
Published	11/11/2024	{{c2::Muscarine}} is an {{c1::agonist}} that activates {{c1::M1-M5}} receptors, and too much can cause {{c3::salivation}}, {{c3::bronchospasm}}, and {…
Published	11/11/2024	{{c1::Atropine and Scopolamine}} act as {{c2::antagonists}} by blocking the effects of {{c2::aCh}} at the {{c4::M1-M5 receptors}}.
Published	11/11/2024	The extracellular domain of Nicotinic AChR is where {{c1::ACh/acetylcholine}} binds.
Published	11/11/2024	When {{c2::2}} ACh molecules bind to the extracellular subunits, the channel changes conformation and opens, allowing {{c1::Sodium ions}} to travel in…
Published	11/11/2024	A typical preparation involved a muscle strip placed into a {{c2::force transducer}}, which was linked to a pen that recorded the {{c1::contraction}} …
Published	11/11/2024	7efb79b4c2284ded9fc3e44f194b9743-ao-1
Published	11/11/2024	7efb79b4c2284ded9fc3e44f194b9743-ao-2
Published	11/11/2024	7efb79b4c2284ded9fc3e44f194b9743-ao-3
Published	11/11/2024	What is the equation to represent Ligand Binding?
Published	11/11/2024	Loewi later identified Vagusstoff as {{c1::Acetylcholine}}.
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