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Unit 1.2 - Protiens
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Published
09/14/2024
The proteome
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Why is the proteome larger than the number of genes?
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Are all genes expressed in all cell types?
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Proteins expressed by a given cell type...
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Key feature in eukaryotic cells
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Why do eukaryotic cells have a system of internal membranes
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Endoplasmic reticulum (ER)
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The golgi apparatus/ Golgi body
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Lysosomes
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vesiscles
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What are synthesised in the ER
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What are synthesised in the smooth endoplasmic reticulum
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where the synthesis of all proteins begins
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How is the rough endoplasmic reticulum formed
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What occurs after the RER is formed (proteins dock with the ER)
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what occurs in the golgi appartus after proteins fuse it
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What is the major modification of proteins
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The synthesis of proteins
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the secretory pathway
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what are many secreted proteins synthesised as
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inactive precursor
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proteolytic cleavage (BK)
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Protein relationship with amino acids
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amino acids structure
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Amino acid classification
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the diversity of r groups results in
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primary structure of proteins
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secondary structure of proteins
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What structure is this?
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What type of beta sheet is this
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what type of beta sheet is this
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what type of protein secondary structure is this
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protein tertiary structure
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interactions between r groups and what can influence them
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protein quaternary structure
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prosthetic group
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ligand
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binding site of a ligand
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what is the ligands effect on the protein
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allosteric interaction (BK)
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where allosteric interactions occur
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allosteric proteins
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-allosteric proteins with multiple sub-units
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what do allosteric enzymes contain
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modulators
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Following the binding of a modulator
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haemoglobin
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haemoglobin pH and temperature benefits
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phosphate
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Protein kinases function
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Protein phosphatase function
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protein phosphorylation
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