Notes in Asynch: Pulm Pharm

To Subscribe, use this Key

Status	Last Update	Fields
Published	10/30/2023	Dexamethasone, hydrocortisone, and prednisone are all examples of {{c1::glucocorticoids}}
Published	10/30/2023	What is the effect of glucocorticoids on production of phospholipase A2?{{c1::Decreased (inhibition)}}
Published	10/30/2023	Glucocorticoids are useful for treating {{c1::inflammatory}} disorders (e.g. gout, rheumatoid arthritis, asthma, IBD)
Published	10/30/2023	What class of drugs acts via suppression of NF-kB signaling? {{c1::Glucocorticoids}}
Published	10/30/2023	{{c3::Adenosine}} is an antiarrhythmic that is less effective in the presence of {{c1::theophylline}} and {{c2::caffeine}} (methylxanthines)
Published	10/30/2023	Selective {{c1::β2}} agonists, such as albuterol, treat {{c2::bronchoconstriction}} in asthma
Published	10/30/2023	Albuterol, pirbuterol, and metaproterenol are {{c1::short}}-acting {{c2::β2 agonists}}
Published	10/30/2023	{{c2::Short}}-acting β2 agonists (e.g. albuterol) are administered as metered-dose inhalers for {{c1::acute}} relief of symptoms
Published	10/30/2023	Inhaled {{c1::corticosteroids}} (e.g. budesonide, fluticasone) can be added as daily maintenance therapy for persistent asthma
Published	10/30/2023	{{c1::Corticosteroids}} treat asthma by blocking {{c2::inflammation}} and {{c3::cellular infiltration}}
Published	10/30/2023	Inhaled corticosteroids (e.g. asthma therapy) inhibit the synthesis of virtually all {{c1::cytokines}}
Published	10/30/2023	What adverse effect is associated with inhaled corticosteroids?{{c1::Oropharyngeal candidiasis}}
Published	10/30/2023	The risk of oropharyngeal candidiasis following inhaled corticosteroids is reduced by {{c1::gargling water and spitting}} after each treatment
Published	10/30/2023	What drug class do fluticasone, budesonide, and beclomethasone belong to?{{c1::Inhaled corticosteroids}}
Published	10/30/2023	What drug class do montelukast and zafirlukast belong to?{{c1::Leukotriene D4-receptor antagonists}}
Published	10/30/2023	What is the route of administration of leukotriene D4-receptor antagonists (e.g. montelukast, zafirlukast)?{{c1::Oral administration}}
Published	10/30/2023	Montelukast and zafirlukast are especially effective at treating {{c1::aspirin-induced}} asthma
Published	10/30/2023	Salmeterol and formoterol are {{c1::long}}-acting {{c2::β2 agonists}}
Published	10/30/2023	Long-acting β2 agonists are used for {{c1::prophylaxis}} in moderate or severe persistent asthma
Published	10/30/2023	Long-acting β2 agonists (e.g. salmeterol) achieve their long duration due to high {{c1::lipid}} solubility
Published	10/30/2023	Long-acting β2 agonists (e.g. salmeterol) are given as a daily inhaler and are always combined with a regimen of {{c1::inhaled corticosteroids}}
Published	10/30/2023	{{c1::Theophylline}} is a methylxanthine that may be used for asthma therapy
Published	10/30/2023	Theophylline causes broncho-{{c1::dilation}} by inhibiting {{c2::phosphodiesterase}}
Published	10/30/2023	What is the route of administration of theophylline (asthma therapy)?{{c1::Oral administration}}
Published	10/30/2023	Theophylline use is limited due to its narrow {{c1::therapeutic index}}
Published	10/30/2023	Theophylline can cause {{c1::tachycardia::HR}}
Published	10/30/2023	Theophylline is metabolized by {{c1::cytochrome P-450}}
Published	10/30/2023	Theophylline blocks the actions of {{c1::adenosine}} (local metabolite)
Published	10/30/2023	{{c1::Omalizumab}} is a monoclonal antibody directed against the {{c2::Fc}} portion of {{c3::IgE}}, preventing mast cell sensitization
Published	10/30/2023	{{c1::Omalizumab}} is used in allergic asthma with increased IgE levels and resistance to inhaled steroids and long-acting β2 agonists
Published	10/30/2023	Nebulized {{c1::ipratropium}} is a muscarinic antagonist that may be used to treat acute, severe asthma exacerbation
Published	10/30/2023	In addition to asthma, ipratropium may also be used to treat {{c1::COPD}}
Published	10/30/2023	Muscarinic antagonists cause broncho-{{c1::dilation}}
Published	10/30/2023	What drug class do ipratropium and tiotropium belong to?{{c1::Inhaled M3 antimuscarinics}}
Published	10/30/2023	Ipratropium and tiotropium primarily affect the {{c1::lungs::organ}} via inhibition of {{c2::M3}} muscarinic receptors
Published	10/30/2023	Which anti-muscarinic (tiotropium or ipratropium) is longer-acting?{{c1::Tiotropium}}
Published	10/30/2023	Mast cells mediate {{c1::allergic}} reactions in local tissues
Published	10/30/2023	To prevent the development of oral thrush after using inhaled corticosteroids, what two interventions can be used?{{c1::Spacer, Rinsing Mouth}}
Status	Last Update	Fields