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MU SOM::Block 3::Anatomy::Neuroendocrinology
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Published
02/08/2025
The hypothalamus can be viewed as the _________ between the limbic, endocrine and _______________ nervous systems
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The hypothalamus extends from the optic chiasm to _______________________________
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Hypothalamus is bilateral and flanks the _________ ventricle
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The hypothalamus mamillary bodies are associated with the _____________ system and invovled with memory
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The infundibulum connects the _________________ to the ______________ gland
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Which of the pituitary lobes grows down from the diencephalon? (is continuous with the the hypothalamus)
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Which pituitary lobe grows up from the roof of the mouth?
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Which part of the pituitary includes the infundibulum?
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Posterior pituitary neurons secrete directly from _______________ to blood stream
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Anterior pituitary neurons secrete through the _______________________
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The paraventricular and supraoptic nuclei are associated with the _______________ pituitary lobe
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The arcuate nucleus is associated with the ______________ pituitary lobe
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Vasopressin and oxytocin are ___________________ pituitary hormones
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ACTH, TSH, PRL, GH, FSH, LH are all ____________________ pituitary horones
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What do trophic hormones do
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The hypothalamus connects to the anterior pituitary via the __________________
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The set of capillary beds in the hypothalamus/pituitary gland are known as the
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The inhibitory hormones released from the hypothalamus are known as
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Hormones realeased from the hypothalamus to control release of other hormones are known as
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Corticotropin releasing hormone causes the release of
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ACTH binds to the adrenal ________ for release of __________
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Cortisol activates the ____________________ of the body
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Thyroid releasing hormon binds to thyrotophs and lactotrophs forrelease of ________ and ____________ from the anterior pituitary gland
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TSH binds to the _____________ for release of
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Lactotroph binding by TRH leads to the release of _________ through the portal venous system
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GHRH binds to _________________ in the anterior pituitary for release of growth hormone
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GNRH binding in the anterior pituitary causes for release of _______ and ________
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FSH and LH bind to the _____________ or _________ and cause for release of _______, __________, and ___________
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Short loop feedback meaning?
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Long loop feedback meaning?
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Cortisol is released in ________ reactions
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What are some situations in which the hypothalmic pituitary adrenal axis may be needed (cortisol)
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What are the CNS functions of the stress response?
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The stress response is activated when ____________ is threatened
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What are peripheral functions of the stress response
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Cortisol release follows a _________ cycle in which highest levels are at around 8AM and lowest levels are between 12am-4am
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One time in which cortisol is released is when blood ___________ is low
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Addisons disease is releated to deficiency in
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Some symptoms of addisons disease are
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Cushin syndrome is caused by ___________ excess
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Some symptoms of cushings syndrome are
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______________ down-regulates TRH receptors in anterior pitutiary inhibiting TSH secretion
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Hyperthyroidism and Hypothyroidism are common cuases of
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Decreased Thyroid hormone in hypothyroidism leads to decreased ____________ feedback on hypothalamus/pitutiary
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Decreased negative feeback on the hypothalamus/pituitary in hypothyroidism results in increased _______ and _____ which leads to overstimulation of th…
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Hashimotos thyroiditis is
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Hyperthyroidism is caused by increased stimulation of thyroid gland which leads to increased production of
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Grave's disease is when there is _______ overstimulation of TSH receptor leading to increased production of TH
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Graves disease causes TH production ____________ of TSH from pituitary
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Somatostatin inhibits release of
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In the liver Growth hormone stimulates production of
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GHRH inhitibits its own secretion from the
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Somatomedins inhibit GH secretion by the
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Both GH and somatomedins stimulate secretion of _________________ by the hypothalamus inhibitin release
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GH direct actions are
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IGF has ___________ half life than GH
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IGF Effects
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rowth hormone is secreted through out _______________
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Near puberty GH release is stimulated by ___________ in females and ___________ in males
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Acromegaly is associated with ___________ excess
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Before puberty FSH lvels are _________ than LH levels
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During puberty there is ____________ secretion of GnRH
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TRH ___________ prolactin secretion while dopamine _______________ prolactin secretion
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Suckling at the breast by an infant stimulates secretion of
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Prlactin is only elevated during __________ and ___________
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Does prolactin also inhibit its own secretion?
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Elevated Estrogen and progesterone levels ____________________ Prolactin receptors
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Prolactin deficiency causes
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Prolactin excess is associated with
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Precocious puberty is a sign of excess
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ADH deficiency is also known as
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Nephrogenic diaetes insipidus is due to the kidneys resistance to
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Symptoms of polydpsia, polyuria, inability to regulate ody temperature, with high serum sodium and osmolarity is associated with central diabetes insi…
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The hypothalmic pituitary adrenal axis is associated with the ______________ nucleus
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Mood swings, depression, diminished sx drive, low blood pressure and fatigue are associated with which hormones and liberin
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Fatigue, cold intolerance, constipation, dry skin and menstrual irregulaties with low thyroid hormone but normal TSH suggest a central ____________ li…
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Headaches, joint pain, increased shoe size, facial feature changes along with elevated IGF-1 levels and pituitary adenoma is associated with what cond…
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Fatigue, weight loss despite increased appetite, palipitations, sweating, proptosis, fine tremor with elevated T3 and T4 with suppressed TSH is associ…
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The ______________ artery is the major blood supply to the brainstem
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Viscera of the neck are supplied by the
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The ____________ artery supplies the spinal cord and lateral neck muscles
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What supplies the trapezius with blood
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On its way to the cavernous sinus the internal carotid artery passes through the carotid canal which is in the ______________ Bone
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What supplies the thyroid sternocleidomastoid, infrayoid muscles, cricothyroid, and upper portion of larynx
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What supplies the soft palate, ear, meninges
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The occipital artery supplies the
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