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Notes in
06ConductingExperimentalStudies
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Experimental Design is used to evaluate {{c1::cause-and-effect}} relationship between a set of independent and dependent variables
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Descriptive Study DesignPurpose: {{c1::describe population}}Example: {{c1::prevalence and incidence}}
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Exploratory Study DesignPurpose: {{c1::find relationship}}Example: {{c1::cross-sectional or prospective}}
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Experimental Study DesignPurpose: {{c1::cause and effect}}Example: {{c1::clinical trials}}
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{{c1::Clinical trials}} describes experimental studies that examine the effect of interventions on patient or community populations; classic e…
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{{c1::Therapeutic Clinical Trial::Type of Clinical Trial}} examine the effect of a treatment or intervention on a particular disease.
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{{c1::Extraneous/Nuisance/Intervening/Confounding variable}} is any factor that is not directly related to the purpose of the study, b…
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{{c1::Internal Validity::Validity}} refers to the potential for confounding factors to interfere with the relationship between the independ…
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{{c1::External validity::Validity}} refers to the extent to which results of a study can be generalized outside the experimental situation&…
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TYPES OF EXPERIMENTAL STUDIES (based on degree of experimental control){{c1::True Experimental Design}}{{c1::Quasi-Experimental Design}}
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TYPES OF EXPERIMENTAL STUDIES (based on how subjects are assigned to groups){{c1::Between-subjects design::Completely randomized designs}}{{c1::…
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{{c1::True experimental designs::Experimental Design}} provides the strongest evidence for causal relationship. Subjects are randomly assig…
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{{c1::Randomized Controlled Trial}} is considered the gold standard of true experimental designs
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A quasi-experimental design lacks: {{c1::random assignment}}{{c1::comparison groups}}{{c1::or both}}
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{{c1::Pretest-posttest control group design::True experimental design}} is used to compare two or more groups ({{c2::Treatment arm/s & Contr…
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{{c1::Posttest-only control group design::True experimental designs}} is done when a pretest is NOT administered to either group. Pretest is imp…
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{{c1::One group pretest-posttest design::Quasi-experimental designs}} involves one set of repeated measures taken before and after treatment on …
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{{c1::Time}} is the independent variable with two levels in one group pretest-posttest design in quasi-experimental designs
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{{c1::One-way repeated measures design over time::Quasi-experimental designs}} involves multiple measurements of the dependent variable taken wi…
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{{c1::Nonequivalent posttest-only control group design::Quasi-experimental designs}} involves a static group comparison: two groups with no rand…
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{{c1::T::T/F}} Once a participant is assigned to the experimental/control group, you cannot transfer them to another group
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Randomization is done to avoid {{c1::non-equivalence}}
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Simple randomization is best used if expected number of participants is {{c1::>200}}
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{{c1::Block Randomization::Randomization}} is designed to randomize participants into groups that result in equal sample size. Done when the number of…
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{{c1::Stratified Randomization::Randomization}} involves identifying relevant population characteristics, and partitioning members of a population int…
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{{c1::T::T/F}} In simple randomization, when baseline characteristics of all participants are NOT available before assignment, using stratified random…
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{{c1::Covariate Adaptive Randomization::Randomization}} is used when new participant is sequentially assigned to a particular treatment group by consi…
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{{c1::Preventive Clinical Trial::Type of Clinical Trial}} - evaluates whether a procedure or agent reduces the risk of developing a disease.
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Components of a Research Question{{c1::Patient/Participants/PopulationsInterventionComparisonOutcome}}
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{{c1::Preventative Clinical Trial::Type of Clinical Trial}} evaluates whether a procedure or agent reduces the risk of developing a disease.
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If a follow up assessment is performed, a study incorporates {{c1::repeated measures}} in its design
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{{c1::Nonequivalent pretest-posttest control group design::Quasi-experimental designs}} are similar to the pretest-posttest control group design, but …
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{{c1::Historical controls::Quasi-experimental designs}} where a nonconcurrent control group may best serve the purpose of comparison when ethical conc…
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Subjects are allocated randomly to independent groups{{c1::Between-subjects design::Between-subjects/Within-subjects design}}
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There is a separate intervention group and control group that will be compared{{c1::Between-subjects design::Between-subjects/Within-subjects design}}
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Subjects act as their own control{{c1::Within-subjects design::Between-subjects/Within-subjects design}}
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Basic structure of repeated measures design{{c1::Within-subjects design::Between-subjects/Within-subjects design}}
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