Notes in ☕️ Coffee + 🏃 Javier + 🧠 Bad Genius

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Published	01/14/2024	In heme synthesis, this starts with A. succinyl CoA and porphobilinogen B. glycine and ALA C. ALA and porphobilinogen D. succinyl CoA…
Published	01/14/2024	Another term for porphobilinogen deaminase A. Uroporphyrinogen III synthase B. Uroporphyrinogen I deaminase C. Hydroxymethylbilane synthase D…
Published	01/14/2024	Majority of adult hemoglobin has this composition A. 2 alpha chains and 2 beta chains B. 2 alpha chains and 2 delta chains C. 2 alpha chains…
Published	01/14/2024	Most of the iron in normal human hemoglobin is distributed in which pool? A. Ferritin  B. Transferrin C. Hemoglobin D. Myoglobin&nbsp…
Published	01/14/2024	Iron absorption occurs in which part of the intestine? A. Proximal duodenum B. Distal duodenum C. Jejunum D. Ileum
Published	01/14/2024	This transporter in enterocyte is non-specific because it transports other cation aside from iron A. NRAMP1 B. DMT1 C. SLC11A2 D. Ferrop…
Published	01/14/2024	Most patients with porphyrins have this signs and symptoms which involves A. hematological B. cutaneous C. visceral organs D. neurological&nb…
Published	01/14/2024	In the heme biosynthesis, which reactions occur in the mitochondria? A. First and second B. Middle and last C. First and last D. Beginning un…
Published	01/14/2024	Porphyria is caused by which of the following? A. Iron deficiency B. Iron overload C. Deficient heme biosynthetic enzymes D. Abundant heme bi…
Published	01/14/2024	Which of the following statements is correct about bilirubin catabolism? A. Bilirubin is converted to biliverdin from hemin B. First pr…
Published	01/14/2024	Phenobarbital is an anticonvulsant (anti-seizure) that induces the cytochrome P450 system. If this drug is inadvertently given to a patient with ac…
Published	01/14/2024	Which of the following enzyme deficiency is classified as hepatic, cutaneous porphyria? A. ALA dehydratase B. UPG I synthase C. UPG decarboxyl…
Published	01/14/2024	Porphyrinogens are colorless because of the absence of ________ bridges. A. methylene B. methyne  C. methane
Published	01/14/2024	A 24-year-old patient was brought to the clinic with acute abdominal pain, depression and extreme weakness. Urine analysis revealed with the presen…
Published	01/14/2024	Which of the following associations is CORRECT? A. Uroporphyrinogen: methyl, propionate B. Coproporphyrinogen: acetate, methyl C. Protop…
Published	01/14/2024	Zinc deficiency will most likely affect the activity of A. ALA synthase B. ALA dehydratase C. PBG deaminase D. ferrochelatase
Published	01/14/2024	Which of the following enzymes is primarily responsible for the abundance of type III porphyrins in the human body? A. UPG III synthase B. UPG…
Published	01/14/2024	Excretion of iron is mainly through which of the following? A. Sweat B. Bile C. Urine  D. Feces
Published	01/14/2024	Retention hyperbilirubinemia is seen in A. hemolytic anemias B. hepatitis C. biliary tract obstruction D. Dubin Johnson syndrome
Published	01/14/2024	Oxidation-reduction reaction of free iron produces?  A. Ferrous iron B. Hydrogen peroxide C. Ferric iron D. Free radicals  …
Published	01/14/2024	Which of the following is a ferrireductase?  a) Ceruloplasmin b) Heme oxygenase c) Hephaestin d) D Cyt B
Published	01/14/2024	In which of the following is iron in its ferrous form?  a.) During its transport with DMT1 b.) From hephaestin to transferrin c.) …
Published	01/14/2024	Which of the following occurs in iron deficiency anemia?  A. More apoferritin is produced. B. More transferrin is produced. C. Less ap…
Published	01/14/2024	Which of the following happens when iron is depleted?  A. In the MRNA of transferrin receptor gene, IRP binds to the 5' region B. In th…
Published	01/14/2024	How does hepcidin regulate iron absorption?  A. Inhibits DMT1 B. Decrease production of tranferrin C. Inhibit conversion ferric to …
Published	01/14/2024	Acholuric jaundice is seen in patients with  A. Hemolytic anemias B. Hepatitis C. Biliary tract obstruction D. Dubin Johnson Syndrome&n…
Published	01/14/2024	Which of the following enzymes requires zinc as cofactor?  A. ALAS B. ALAD C. PBG deaminase D. Ferrochelatase
Published	01/14/2024	Which of the following is true for erythroid ALA synthatase?  a. Heme inhibits its transport from cytosol. b. Heme inhibits its activity…
Published	01/14/2024	Acquired porphyria is due to ________ toxicity.  A. Magnesium B. Lead C. Iron D. Zinc
Published	01/14/2024	Phenobarbital is an anticonvulsant (anti-seizure) which induces the cytochrome p450 system. If this drug is inadvertently given to a patient with …
Published	01/14/2024	Enzymes required for heme synthesis can be found in:  A. Cytosol B. Mitochondria C. Both D. None
Published	01/14/2024	Porphyrinogen rings consists of 4 pyrrole rings linked by:  A. Methylene bridges B. Methyne bridges C. Methoxy bridges D. Met…
Published	01/14/2024	A 6-year old boy presents with bullae and vesicles in his arms after one week of soccer training under the heat of the sun. His father has a simil…
Published	01/14/2024	Heme oxygenase is an enzymatic complex responsible for heme catabolism in the microsome. Which of the following is one of its product?  …
Published	01/14/2024	Which is true about Gilbert Syndrome  A. Fatal B. Form of unconjugated hyperbilirubinemia C. Common among females D. Requires pho…
Published	01/14/2024	Direct hyperbilirubinemia is associated with which of the following disorders?  A. Physiological Neonatal Jaundice B. Type I Crigle…
Published	01/14/2024	A 24 year old patient was brought to the clinic with compliants in acute abdominal pain, depression and extreme.... Urine examination presented an…
Published	01/14/2024	Which statement is false  A. ALA synthase is synthesised in the mitochondria B. Uroporphyrinogen produced is usually in type III is…
Published	01/14/2024	Child develops anemia from playing with moth balls. The mother claimed that her child is glucose-6- phosphate dehydrogenase defficient.what is the…
Published	01/14/2024	A deep jaundice 2 days old baby present with lethargy and seizures. Which of the following is most likely to happen?  A. Absent urine ur…
Published	01/14/2024	Which of the following transports iron across macrophages?A. DMT 1 B. NRAMP 1 C. Transferrin D. Ferroportin
Published	01/14/2024	Iron is in the ferric form in which area?A. Absorption of inorganic iron at the apical sites of enterocytes B. Absorption of heme iron at macrop…
Published	01/14/2024	Ferric iron is reduced to Ferrous by? A. Hephaestin B. Hepcidin C. Ceruloplasmin D. Steap 3
Published	01/14/2024	How is iron regulated when there is iron deficiency anemia? A. Tranferrin receptors are synthesized B. Apoferritin are synthesized C. Hepcid…
Published	01/14/2024	Iron absorption is enhanced by? A. Coffee B. Milk C. Vitamin C D. Beans
Published	01/14/2024	Zinc deficiency will most likely affect the action of? A. ALA Synthase B. ALA dehydratase C. PBG deaminase D. Ferrochelatase
Published	01/14/2024	Lead poisoning affects heme metabolism because it disrupts the activity of? A. ALAS B. ALAD C. Ferrochelatase D. Both A and C …
Published	01/14/2024	Phenobarbital is an anticonvulsant (anti-siezure) which induces the Cyt P450 system. If this drug this advertently given to a patient with acute p…
Published	01/14/2024	Heme oxygenase system can be found in? A. Cytoplasm B. Mitochondria C. Microsomes D. Endoplasmic Reticulum
Published	01/14/2024	Heme oxygenase is an enzymatic complex responsible for heme catabolism in the microsome. Which of the following is one of its products? A. CO B. CO…
Published	01/14/2024	A 24-year-old patient was brought to the clinic, with complaints of acute abdominal pain, depression, and extreme weakness. Urine examination prese…
Published	01/14/2024	Which of the following is classified as hepatic porphyria? A. Protoporphyria B. Porphyria cutaneatarda C. Congenital erythropoietic D. X-link…
Published	01/14/2024	Hemin is an Fe3+ and chloride containing Protoporphyrin IX and is used to alleviate porphyria. Which of the following is true? A. Acts as a n…
Published	01/14/2024	Child develops anemia from playing with moth balls. The mother claimed that her child is glucose-6- phosphate dehydrogenase deficient. What is the …
Published	01/14/2024	A deeply jaundiced 6-hour old newborn became lethargic and had seizures. Baby is A(Rh+) mother O(Rh+). Which of the following findings is consisten…
Published	01/14/2024	Type III Protoporphyrin is abundant in nature because of the activity of? A. UPG III synthase B. UPG decarboxylase C. CPG oxidase D. PPG oxid…
Published	01/14/2024	The formation of Coproporphyrinogen is catalyzed by a/an? A. Oxidoreductase B. Lyase C. Ligase D. Hydrolase
Published	01/14/2024	The side chains of a porphyrin ring are derived from?A. Glycine B. Succinyl CoA C. Both A and B D. Neither A and B
Published	01/14/2024	Acholuric jaundice is seen in? A. Hemolytic anemia B. Hepatitis C. Biliary tract obstruction D. Dubin Johnson syndrome
Published	01/14/2024	An 8-year old boy is brought to a dermatologist due to appearance of vesicles and bullae on his face and arms following a weeklong exposure to sun …
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