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Notes in
Dyslipidemias LECTURE 25
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01/07/2025
arcus senilis? (Corneal arcus)corneal arcus; present in >50% of patients {{c1::>50}}can be a sign of {{c1::dyslipidaemia}} in patients <…
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01/07/2025
What are lipoproteins?What is their function?What do they contain?fats do not mix with {{c1::water}}lipoprotein molecules carry {{c1::fat}} in bl…
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01/07/2025
structure of lipoproteinssurface:(free) {{c1::cholesterol}}- {{c1::apolipoproteins}}- {{c1::phospholipid}}core:- {{c1::cholesterol}}- {{c1::triglyceri…
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01/07/2025
lipoprotein subtypes (5){{c1::}}
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basic cholesterol pathway{{c1::precursor}} = Acetyl-CoAwhich is metabolised to {{c1::HMG-CoA}}metabolised to {{c1::Mevalonate}}by enzyme {{c…
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exogenous pathway: how lipids are transported from {{c1::gut to liver}}dietary fats transported from gut in {{c1::Chylomicrons}}triglyceride comp…
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01/07/2025
endogenous pathway (how cholesterol moves from {{c1::liver to tissues)}}liver produces {{c1::VLDL and LDL}}{{c1::triglyceride}} component of…
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01/07/2025
reverse pathway (how cholesterol moves from {{c1::tissues back to liver}})some free cholesterol in tissues is taken up into {{c1::HDL}}This is th…
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01/07/2025
what is the 'ideal' lipid profile?:total cholesterol:{{c1::low LDL}}{{c1::high HDL}}{{c1::low total/HDL}} ratio{{c1::low triglyceride}}
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01/07/2025
causes of secondary dyslipidaemia{{c1::diabetes}} mellitus - most common{{c1::hyperthyroidism}}{{c1::chronic kidney}} disease{{c1::chronic l…
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