Notes in 02 Adult Glomerulonephritis

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Published	11/07/2023	Nephrotic syndrome pathogenesis:You have an excessive leak of {{c1::protein}} through the glomerular capillary wall into the urinary space due to disr…
Published	11/07/2023	In nephrotic syndrome, you have {{c1::low}} serum albumin because you lose it in the {{c1::urine}}This causes the liver to produce {{c2::more}} p…
Published	11/07/2023	In nephrotic syndrome, you have edema/anasarca because you have {{c1::decreased}} plasma oncotic pressure (due to protein loss in the urine) -> fil…
Published	11/07/2023	Nephritic syndrome pathogenesis:Active {{c2::inflammation}} and {{c2::injury}} within the glomerulus -> glomerular damage and loss of capillary sur…
Published	11/07/2023	Nephritic syndrome's urine shows {{c1::dysmorphic}} RBCs
Published	11/07/2023	In nephritic syndrome, you have reduced renal blood flow -> RAAS activation -> Salt and water retention -> {{c1::edema}} + {{c1::hypertension…
Published	11/07/2023	In nephritic syndrome, the glomerular capillary wall injury is {{c1::focal}} and in nephrotic syndrome it is the {{c1::entire}} capillary wall that is…
Published	11/07/2023	{{c1::Rapidly Progressive Glomerulonephritis}} presents with rapid deteioration of renal function, low urine output, hematuria, HTN, and edema
Published	11/07/2023	Common causes of RPGN: {{c1::Anti-glomerular basement membrane nephritis}}, ANCA vasculitis
Published	11/07/2023	Lupus nephritis most commonly occurs in {{c1::young females}}Minimal change disease is the most common cause of nephrotic syndrome in {{c1::young chil…
Published	11/07/2023	85f8085330674ce0852aa0c55da2d3b3-oa-1
Published	11/07/2023	1c1f8250a23546b892c6486f7c54c4b7-oa-1
Published	11/07/2023	Hypertension + edema + decreased GFR + low proteinuria (<3g) + active urine sediment (dysmorphic RBCs) = {{c1::Nephritic syndrome::diagnosis}}
Published	11/07/2023	Young age + sudden onset nephrotic syndrome (hypoalbuminemia, proteinuria, fat bodies in the urine) + normal BP + normal renal function = {{c1::minima…
Published	11/07/2023	You treat minimal change disease by {{c1::corticosteroids}}
Published	11/07/2023	Diagnosis: Shorter time period = {{c1::IgA nephropathy}}Longer time period (2-3 weeks ago was infection) = {{c1::Post infectious glomerulonephrit…
Published	11/07/2023	Complement levels are low only in {{c1::postinfectious glomerulonephritis::kidney pathology}}
Published	11/07/2023	Only {{c1::50}}% of people with IgA nephropathy have an elevated IgA level
Published	11/07/2023	A = {{c1::IgA nephropathy (IgA deposits and there are some of the nodules on LM)}}B = {{c1::Post-infectious glomerulonephritis (complement deposi…
Published	11/07/2023	You treat post infectious glomerulonephritis by {{c1::supportive care (Antibiotics, BP control, diuretic, low salt diet)}}
Published	11/07/2023	53f066fe3d30457a9c02d5ea734b8914-oa-1
Published	11/07/2023	If you suspect that you have nephrotic syndrome, you should do a {{c1::kidney biopsy::next steps}}
Published	11/07/2023	1373f4f60ebf4340b522125475cc1dae-oa-1
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