Notes in 01. Pulm Neoplasms

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Published 06/26/2023 what is the most common cause of cancer related deaths? {{c1::lung cancer}} in both males and females
Published 06/26/2023 Lung cancer → risk factors obj 1{{c1::smoking}} → primary risk factor → responsible for 80-90% of lung cancers clear dose response relations…
Published 06/26/2023 classification of lung cancer MC → {{c1::non-small cell lung cancer}} 75-80%small cell lung cancer 15-20% others {{c2::adenocarcin…
Published 06/26/2023 classification of lung cancer adenocarcinoma → {{c1::lepidic, acinar, basillarly}}adenosquamous carcinoma squamous cell carcinoma →&nbs…
Published 06/26/2023 histology and presentation squamous cell → 95% are {{c1::smokers}}; cancer is {{c1::centrally}} located and can caviate → associated wi…
Published 06/26/2023 signs and symptoms presentation can be {{c1::subtle}} and physical exam may be unremarkable if central airway tumor a typical symptom i…
Published 06/26/2023 symptoms of lung cancer {{c1::cough}}weight {{c1::loss}}dyspneachest pain hemoptysis bone pain 
Published 06/26/2023 superior vena cava syndrome {{c1::centrally located}} massess obstructive the SVC obstruction causes symptoms that commonly include → a sens…
Published 06/26/2023 pancoast syndrome lung cancers arising in the {{c1::superior sulcus}} → {{c1::apical}} lung cancer Pain (usually in the shoulder)&…
Published 06/26/2023 paraneoplastic syndrome → syndrome → MC cancer → mechanism obj 3 hypercalcemia → {{c1::squamous cell}} then adenocarcinoma, small cell …
Published 06/26/2023 nail clubbing can be found in normal population multiople pulmonary diseases → ILD, pulmonary fibrosis, sarcoidosis, CF, chronic {{c1::…
Published 06/26/2023 carcinoid tumor well differentiated neuroendocrine tumor (NET) → typical/low grade and atypical/intermediate grade arises from → {{c1::…
Published 06/26/2023 small cell and large cell NET → aggressive course and high rate of {{c1::mitosis}} compared to pulmonary carcinoids 
Published 06/26/2023 DIPNECH → diffuse idiopathic pulmonary neuroendocrine cell hyperplasia generalized proliferation of pulmonary neuroendocrine cells that may be co…
Published 06/26/2023 solitary pulmonary nodule: risk for malignancy? obj 2defintion → a solitary pulmonary nodule (SPN) is defined as a single {{c1::intraparench…
Published 06/26/2023 benign neoplasms
Published 06/26/2023 calcification pattern and malignancy BenignA → {{c1::central}}B → {{c1::laminated}}C → {{c1::diffuse}}D → {{c1::popcorn}}A th…
Published 06/26/2023 solid and ground-glass components partly {{c1::solid}} lesions w/ ground-glass components → malignancy rate of {{c1::63%}}non-solid → only&n…
Published 06/26/2023 which is better at reducing mortality → Low dose CT (LDCT) vs Chest X ray{{c1::LDCT}} reduced mortality in {{c1::high-risk}} population both…
Published 06/26/2023 management of lung cancer {{c1::tissue}} diagnosis → CT guided biopsy, bronchoscopy staging PET CT and sometimes brain MRI TUMOR B…
Published 06/26/2023 Staging and treatment non-small lung cancer obj 5{{c1::TNM}} staging. Staging I, II, III, and IV resection is favored for stages →…
Published 06/26/2023 summary of long staging graph larger tumor → {{c1::higher}} stage contralateral {{c1::lymphadenopathy}} → higher stage {{c1::media…
Published 06/26/2023 EVUS vs Mediastinoscopy in pts w/ high suspicion of N2,3 invovlement, either by discrete mediastinal lymph node enlargement of PET uptake, a&nbsp…
Published 06/26/2023 bronchoscopy vs CT guided biopsy (MC to least common) transbronchial biopsy, needle aspirate, bronch lavage {{c1::central lesions}}, diagnos…
Published 06/26/2023 survival small cell lung cancer OBJ 7limited stage disease → median survival is 15-20 months w/ a five year survival of {{c1::10-13%}}extens…
Published 06/26/2023 read through about adenocarcinomas and drugs 
Published 06/26/2023 programmed cell death 1 (PD-1) is a {{c1::negative}} costimulatory receptor expressed primarily on surface of activated T cells PD-L1 expres…
Published 06/26/2023 65 yo F Smoker, w/ hx of weight loss, left ear pain and hemoptysis → cancer or no? granulomatosis w/ polyangiitis → {{c1::Wegener's}}
Published 06/26/2023 TNM staging is all about is it {{c1::resectable}}? → referring to {{c1::NSCLC}}
Published 06/26/2023 double digit are {{c1::hilum}}single digit are {{c1::mediastinal}}
Published 06/26/2023 pulmonary function requirements for pulmonary resection 
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