Notes in Cellular Pathology of CNS

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Status	Last Update	Fields
Published	12/09/2024	Acute Neuronal Injury{{c1::"Red neuron"}} →Earliest ({{c2::6-12 h::how many hours?}}) morphologic markers of neuronal cell death
Published	12/09/2024	Acute Neuronal InjuryCommon causes: {{c1::Hypoxia/ischemia }} {{c2::Severe hypoglycemia}}
Published	12/09/2024	Acute Neuronal InjuryPathologic Changes: {{c1::Shrinkage of cell body, pyknosis of nucleus}}{{c1::disappearance of nucleolus}}{{c1::loss of Nissl…
Published	12/09/2024	{{c1::Subacute and Chronic Neuronal Injury}}Neuronal death that occurs as a result of a progressive disease (months to years)
Published	12/09/2024	Axonal Reaction is  seen during {{c1::regeneration}}
Published	12/09/2024	Morphologic characteristics of Axonal Reaction{{c1::Peripheral}} displacement of nucleus{{c1::enlargement}} of the cell body and nucleolusdispersion o…
Published	12/09/2024	Conditions that can indicate Neuronal Inclusions: {{c1::Aging}} {{c1::Inborn errors ofmetabolism}}{{c1::genetic disorders}} {{c1::Viral infection…
Published	12/09/2024	{{c1::Wallerian Degeneration}} : Degenerationofaxonsafterdisruptionofnervefibers
Published	12/09/2024	{{c1::Gliosis}}: Most important histopathologic marker of CNS injury
Published	12/09/2024	{{c1::Gliosis}}: Hypertrophy and hyperplasia of astrocytes
Published	12/09/2024	{{c1::Gliosis}}: Nuclei enlarge, become vesicular, and may develop prominent nucleoli
Published	12/09/2024	{{c1::Gliosis}}: Brightpink cytoplasm due to increased {{c2::GAP}}
Published	12/09/2024	{{c1::Gliosis}}: Numerous stout, ramifying process (reactive or gemistocytic astrocytes)
Published	12/09/2024	Alzheimer Type II astrocyte: {{c1::Gray matter}} cell with {{c2::2-3}}x size nucleus
Published	12/09/2024	Alzheimer Type II astrocyte: {{c2::Pale::Brightly/Pale}} staining {{c1::central chromatin}}
Published	12/09/2024	{{c2::Alzheimer Type II astrocyte}}: Intranuclear {{c1::glycogen}} droplet
Published	12/09/2024	{{c2::Alzheimer Type II astrocyte}}: Seen in {{c1::hyperammonemia}}
Published	12/09/2024	{{c1::Rosenthal fibers}} : Thick, elongated, brightly eosinophilic, irregular structures that occur within {{c2::astrocytic processes}}
Published	12/09/2024	{{c1::Rosenthal fibers}} : Contain {{c2::αβ-crystallin}}, {{c2::hsp27}}, and {{c2::ubiquitin}}
Published	12/09/2024	{{c1::Corpora amylacea}} : Round, faintly basophilic, PAS (+), concentrically lamellated structures
Published	12/09/2024	{{c1::Corpora amylacea}} : Contains {{c2::HSP}}, {{c2::ubiquitin}}, and {{c2::GAG}}
Published	12/09/2024	Reaction of {{c2::MICROGLIA}} to injury:{{c1::Proliferation }}Development of {{c1::elongated nuclei }}Forming {{c1::aggregates}} around smal…
Published	12/09/2024	Reaction of {{c2::OLIGODENDROCYTES}} to injury:Inclusions {{c1::Progressive multifocal leukoencephalopathy}} {{c1::Alpha-synuclein in multiplesys…
Published	12/09/2024	Reaction of {{c1::Ependymal cells}} to injury:{{c2::Ependymal granulations}} {{c2::Viral inclusions(CMV)}}
Status	Last Update	Fields