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Notes in 04. Tetanus

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Published 06/26/2023 Tetanus Organism {{c1::Clostridium tetani}}Gram {{c1::positive}} anaerobic/aerobic? → {{c1::anaerobic}}spores/cocci? → {…
Published 06/26/2023 Tetanus stats globally → {{c1::>50,000 deaths}}United States → {{c1::264}} deaths from 2009-2017 
Published 06/26/2023 Tetanus → pathogenesis target cell → {{c1::neurons}}produces {{c1::metalloproteasse}} tetanus toxinaxonal transport to {{c2::brain…
Published 06/26/2023 tetanus → symptoms dysphagia rigid {{c1::abdomen}} apneic episodes {{c1::stiff neck}}{{c1::opisthotonus}} → severe spasms causing …
Published 06/26/2023 can also be seen w/ severe meningitis 
Published 06/26/2023 Post exposure treatment wound care tetanus immunoglobulin (TIG) → can bind tetanus toxin if toxin has not already bound to {{c1::nerve …
Published 06/26/2023 3142255c6d9b480986e31d2e121c6923-oa-1
Published 06/26/2023 3142255c6d9b480986e31d2e121c6923-oa-2
Published 06/26/2023 Disease treatment for tetanus {{c1::Metronidazole}} or Penicillin G Cefazolin Ceftriaxone Doxy, clindamycin Symptomatic and s…
Published 06/26/2023 Tetanus → prognosis 5-50% mortality rate worldwide 20% in US Lasting {{c1::sequela}} is possible
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