Notes in Week 2 - Antiparasitic Agents

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Published 01/16/2025 {{c1::Ivermectin}} is the first-line pharmacological treatment for infections by {{c2::Strongyloides stercoralis}} and {{c2::Oncho…
Published 01/16/2025 In pregnant patients, the first-line antiparasitic treatment for a nematode infection is {{c1::pyrantel pamoate}}
Published 01/16/2025 {{c3::Pyrantel pamoate}} is an {{c1::acetylcholine}}-receptor {{c1::agonist}} that results in {{c2::spastic}} paralysis
Published 01/16/2025 {{c3::Ivermectin}} is a {{c1::GABA}}-receptor {{c1::agonist}} that increases intracelluar {{c3::Cl-}}, resulting in {{c2::flaccid}} paralysi…
Published 01/16/2025 {{c3::Praziquantel}} increases the cell membrane's permeability to {{c1::Ca2+}} resulting in {{c2::spastic}} paralysis
Published 01/16/2025 What type of meals increase the oral bioavailabillity of microtubule inhibitors (e.g. albendazole)?{{c1::Fatty meals}}
Published 01/16/2025 What class of drugs is co-administered with albendazole s to manage inflammation caused by neurocysticercosis?{{c1::Corticosteroids}}
Published 01/16/2025 {{c1::Diethylcarbamazine}} is a microtubule inhibitor that immobilizes parasitic microfilariae
Published 01/16/2025 Ivermectin can only be used to treat the {{c1::microfiliarae}} form of Onchocerca volvulus
Published 01/16/2025 Corticosteroids should not be co-administered to treat infections by {{c1::Strongyloides stercoralis}}
Published 01/16/2025 {{c1::Pyruvate:ferredoxin oxidoreductase (PFOR)}} is an enzyme found in anaerobic organisms that activates metronidazole into its …
Published 01/16/2025 {{c1::Nitazoxanide}} is the prodrug of tizoxanide
Published 01/16/2025 Nitazoxanide can be used to treat Cryptosporidium spp. and {{c1::Giardia lamblia}}
Published 01/16/2025 {{c1::Tizoxanide}} is an antiparasitic agent that inhibits {{c2::pyruvate:ferrodoxin oxidoreductase (PFOR)}}
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