Review Note
Last Update: 08/30/2023 12:42 AM
Current Deck: ACMS Study Guide Deck::A. Cancers
PublishedCurrently Published Content
Front
Describe pathophysiology of AFX and risk factors
Back
Fibrohistiocytic mesenchymal origin
• C->T mutations in dipyrimidines in the p53 and TERT promoter genes (thus
driven by UV-induced mutations)
• Sun damaged skin of elderly
• Other risk factors: previously radiated skin, immunosuppressed (organ
transplant)
• C->T mutations in dipyrimidines in the p53 and TERT promoter genes (thus
driven by UV-induced mutations)
• Sun damaged skin of elderly
• Other risk factors: previously radiated skin, immunosuppressed (organ
transplant)
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