Review Note
Last Update: 09/11/2023 08:56 PM
Current Deck: L38 Bone and Joints Path II
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Text
What is the third stage of Paget disease of bone (osteitis deformans)?
{{c1::Osteoblastic (sclerotic)}}
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LN
Osteolytic phase (Osteitis Deformans)
Predominant osteoclastic activity → > 100 nuclei lytic lesions ↑ Bone resorption markers
Mixed Phase Osteoclastic + osteoblastic activity
LCT with osteoprogenitor cells & many blood vessels
New woven bone formation → thin & thick bony trabeculae
Blastic/ Osteosclerotic/ Burnout Phase
Predominant osteoblastic activity Jigsaw/ Mosaic pattern of lamellar bone with coarsely thickened trabeculae & irregular cement lines Lack structural ability → bones prone to fx
Osteolytic phase (Osteitis Deformans)
Predominant osteoclastic activity → > 100 nuclei lytic lesions ↑ Bone resorption markers
Mixed Phase Osteoclastic + osteoblastic activity
LCT with osteoprogenitor cells & many blood vessels
New woven bone formation → thin & thick bony trabeculae
Blastic/ Osteosclerotic/ Burnout Phase
Predominant osteoblastic activity Jigsaw/ Mosaic pattern of lamellar bone with coarsely thickened trabeculae & irregular cement lines Lack structural ability → bones prone to fx
Lecture Notes
Missed Questions
Pathoma
Boards and Beyond
First Aid
Sketchy
Pixorize
Physeo
OME
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