Review Note
Last Update: 09/14/2023 09:38 PM
Current Deck: EthanKi Term 1::FOM::Week 3::Protein and Lipid Metabolism Lecture
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how protein Ends up in different compartments
{{c1::Proteins to be secreted}} = carbohydrate side chain on serine / threonine residues within specific AA
{{c1::Cargo to be degraded }} = Tagged for lysosomes/proteasomes by ubiquitination on lysine resides
{{c2::RER signal or start transfer signal = 20-30 hydrophobic AA at beginning of protein-}} when this is recognized, ribosome translocates to the ER to continue protein synthesis
{{c2::STAY Inside ER lumen}} = glycosylation of asparagine
{{c1::Proteins to be secreted}} = carbohydrate side chain on serine / threonine residues within specific AA
{{c1::Cargo to be degraded }} = Tagged for lysosomes/proteasomes by ubiquitination on lysine resides
{{c2::RER signal or start transfer signal = 20-30 hydrophobic AA at beginning of protein-}} when this is recognized, ribosome translocates to the ER to continue protein synthesis
{{c2::STAY Inside ER lumen}} = glycosylation of asparagine