Review Note
Last Update: 10/02/2023 08:21 AM
Current Deck: All Exams P1::IE #3::Pharm 111 Exam 3
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how does arrestin form a signaling platform
{{c1::1) when an agonist binds to the GPCR, the g protein alpha subunit dissociates and leaves}}
{{c2::2) the GRK phosphorylates the receptor }}
{{c3::3) the beta arrestin binds to the phosphorylated site }}
{{c4::4) internalization (endocytosis) of the receptor is triggers}}
{{c5::5) with the receptor now inside the cell, different intracellular proteins can bind to the receptor via beta arrestin }}
{{c6::6) this allows for cross communication to occur between different pathways in the cell }}
{{c1::1) when an agonist binds to the GPCR, the g protein alpha subunit dissociates and leaves}}
{{c2::2) the GRK phosphorylates the receptor }}
{{c3::3) the beta arrestin binds to the phosphorylated site }}
{{c4::4) internalization (endocytosis) of the receptor is triggers}}
{{c5::5) with the receptor now inside the cell, different intracellular proteins can bind to the receptor via beta arrestin }}
{{c6::6) this allows for cross communication to occur between different pathways in the cell }}
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