Review Note
Last Update: 10/21/2023 10:11 PM
Current Deck: All Exams P1::Pharm116 Exam#2::Handout 2
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Regulation in Glycolysis
- {{c1::PFK enzyme}} is rate limiting or where regulation occurs
- PFK is allosteric enzyme
- AMP- {{c2::allosteric activator → R state}}
- ATP- {{c2::allosteric inhibitor → T state }}
- ATP binding affinity for PFK active site {{c3::much better}} than ATP binding affinity for allosteric site so it {{c3::(only binds allosteric at high concentration of ATP)}}
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