Review Note
Last Update: 10/22/2023 09:22 PM
Current Deck: All Exams P1::Pharm116 Exam#2::Handout 3
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Reaction 3: Isocitrate Dehydrogenase (Irreversible)
- {{c1::Isocitrate 6C + NAD+}} → {{c1::NADH + H+ + CO2 + alpha-Ketoglutarate 5C}}
- Hydride ion transfer
- Dehydrogenase usually involve {{c2::oxidation-reduction reactions}}
- Oxidative decarboxylation reaction
- {{c4::Oxidation}}- {{c3::electrons transferred to NAD+ to make NADH}}
- {{c4::Decarboxylation}}- {{c3::CO2 released}}
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