Review Note

Last Update: 11/06/2023 11:02 PM

Current Deck: BIOC 405

Published

Fields:

Front

Why is HbS so common?

Back

Mixed HbA:HbS RBCs have properties that protect heterozygotes from malaria parasites. Possibly due to quick removal of infected cells or because infected HbA:HbS cells damage the parasites.

Either way heterozygotes confer advantage or homozygotes:

HbA homozygotes succumb to malaria
HbS homozygotes die early because of sickle cell anemia

Tags:

Biochem::Protein_Structure

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