Review Note
Last Update: 11/06/2023 11:02 PM
Current Deck: BIOC 405
PublishedCurrently Published Content
Front
What are the fundamentals of the fluid mosaic model of membrane organization?
Back
DYNAMIC, NOT UNIFORM throughout cell
The lipid bilayer is a thin 2D fluid:
The lipid bilayer is a thin 2D fluid:
- Mosaic of lipids, proteins, and carbohydrates
- Non-covalent interactions
- Lipids and proteins diffuse laterally through membrane (lipids ~ 10-8 to 10-9 cm2/s, integral membrane proteins ~ 10-9 to 10-11 cm2/s)
- Asymmetric composition: lipids (dynamic symmetry), peripheral and integral proteins (absolute symmetry), glycosylation (lipids and proteins on outer membrane)
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