Review Note

Last Update: 11/15/2023 07:12 PM

Current Deck: All Exams P1::IE #6::PHAR117::Modified Release Products

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Polymer Dissolution/Erosion
  • drug is {{c1::coated or entrapped}} in polymer which is {{c1::initially insoluble but becomes soluble over time due to hydrolysis or ionization (pH change)}}
  • Examples:
    • {{c2::Partially esterified copolymers of methyl vinyl ether}}
    • {{c2::(Meth)acrylic acid/(meth)acrylate copolymers}}
    • {{c2::Cellulose acetate phthalate (CAP)}}
    • {{c2::Hydorxypropyl methylcellulose phthalate (HPMCP)}}
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