Review Note
Last Update: 11/18/2023 09:08 PM
Current Deck: Jack's EPPP flashcards (in progress)::Jack Brain Chart EPPP - Prepjet
Published
Fields:
Front
Physiology: Hindbrain: Locus Coeruleus (Function disorder/treatment, drugs, side effects)
Back
- Function:
- The primary function of the locus coeruleus is to regulate the amount of noradrenaline/Norepinephrine in the forebrain. Thus, at a behavioral or systems level, the function of the locus coeruleus critically depends upon the dynamic interaction between the released noradrenaline and neuronal activity in its multiple target areas.
- Disorder/Treatment:
- Parkinson's mood symptoms - loss of neurons in this area results in lower levels of norepinephrine = non-motor symptoms of depression, cognitive deficits and sleep disturbances
- Alzheimer's - first area of the brain to be affected by Alzheimer's disease and shows abnormalities before the appearance of symptoms
- Neurocognitive Disorder:
- linked to neurocognitive disorder with Lewy bodies
- Neurocognitive disorder due to Parkinson's disease
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