Review Note
Last Update: 12/13/2023 07:29 PM
Current Deck: Jaden's Anki::Heme::Lecture Videos::Week 2
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Drug resistance mechanisms for methotrexate:
Decreased drug transport via reduced {{c1::folate}} carrier
Decreased cytotoxic MTX {{c2::polyglutamate}} formation
Increased levels of target enzyme {{c3::DHFR}} through gene {{c4::amplification}}
Altered {{c3::DHFR}} protein with reduced affinity for MTX
Decreased drug transport via reduced {{c1::folate}} carrier
Decreased cytotoxic MTX {{c2::polyglutamate}} formation
Increased levels of target enzyme {{c3::DHFR}} through gene {{c4::amplification}}
Altered {{c3::DHFR}} protein with reduced affinity for MTX
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Lecture Notes
Missed Questions
Pathoma
Boards and Beyond
First Aid
Sketchy
Sketchy 2
Sketchy Extra
Picmonic
Pixorize
Physeo
Bootcamp
OME
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