Review Note
Last Update: 12/13/2023 09:07 PM
Current Deck: 1 CRNA::Apex Ankisthesia::Ankisthesia::M&M::42 Pediatric Anesthesia
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The primary determinant of cardiac output in a neonate is {{c1::heart rate}}.
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Cardiac stroke volume is relatively fixed by
the immature, noncompliant left ventricle in
neonates and infants. The cardiac output is therefore very sensitive to changes in heart rate
Anesthetic overdose, or hypoxia can
quickly trigger bradycardia and profound reductions in cardiac out. The sympathetic nervous system and baroreceptor reflexes are not fully mature. The infant cardiovascular system displays a blunted response to
exogenous catecholamines
Intravascular volume depletion in neonates and infants may be signaled by hypotension without tachycardia
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