Review Note
Last Update: 12/28/2023 09:26 PM
Current Deck: Duke Pathoma::03_cancer
Published
Fields:
Front
How is the Ras pathway normally activated?
Back
1) Ras is associated with growth factor receptor on cytoplasmic surface of cell membrane; bound to GDP
2) Receptor activation causes GDP to be replaced by GTP ("activation")
3) Activated Ras send signals to the nucleus via the Raf/MEK/ERK pathway
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