Review Note
Last Update: 12/28/2023 09:26 PM
Current Deck: Duke Pathoma::06_WBC
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Front
What is a lacunar cell?
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A lacunar cell is a Reed-Sternberg cell that can be observed in the lake-like spaces between fibrotic bands - seen in the nodular sclerosing form of hodgkin lymphoma.
Several "lacunar cells" are present. They are characterized by multilobated nuclei, small nucleoli, and abundant, pale cytoplasm that often "retracts" during tissue fixation and sectioning, leaving the nucleus in what appears to be an empty space (lacune). "Mummified cells" are neoplastic cells that contain condensed cytoplasm and pyknotic reddish nuclei. A "mummified" Reed-Sternberg cell is in the upper left corner.
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