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Last Update: 01/14/2024 12:31 PM

Current Deck: ✪ YEAR 1::★ 1st Bimonthly::✦ Exam #4: Tissue Biology: Epithelium & CT::✧ Nerve Tissue

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Text
{{c1::Microglia}} fuse to form multinucleated giant cells in the CNS when infected by {{c2::HIV}}
Extra
- initially HIV infected monocytes cross BBB and become perivascular macrophages that release HIV derived proteins / inflammatory cytokines, microglia form nodules around these macrophages and fuse to form giant cells and nodules

- Chronic HIV encephalitis is due to nodules of these multinucleated microglia
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#AK_Original_Decks::Step_1::Zanki_Step_Decks::Zanki_Neurology::Kaplan_Neuroscience #AK_Step1_v11::#B&B::15_Neuro::01_Intro::01_Cells_of_the_Nervous_System #AK_Step1_v11::#FirstAid::10_Hematology_Oncology::02_Anatomy::06_Macrophages::Specific_Tissues::Microglial_Cells

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