Review Note

Last Update: 01/14/2024 12:31 PM

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Which of these naturally occurring substances is the principal inhibitor of fibrinolysis?

A. Antithrombin III

B. Thrombomodulin

C. Alpha-1 antitrypsin

D. Alpha-2 antiplasmin
Back
D
you've gots to know
Plasmin degrades stable fibrin into fibrin breakdown products in a process called Fibrinolysis. The principal inhibitor of Fibrinolysis therefore is a one that directly affects the activity of Plasmin. Figure 18-14 in Boron shows the Fibrinolytic Cascade and it is indicated there that Alpha 2 – AP (Antiplasmin) directly inhibits Fibrinolysis activity of Plasmin.
title
super lenghty explanation
mneumonic

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