Review Note

Last Update: 02/03/2024 08:38 PM

Current Deck: Micro 1

Published

Fields:

Front
Agents that inhibit DNA metabolism through nucleic acid synthesis inhibition
Back
a)  Novobiocin: Inhibits DNA gyrase cannot synthesize DNA → death

b)  Quinolones: Inhibits DNA gyrase
(1) Ciprofloxacin, Nalidixic Acid
(2) Nitrofurans, Metronidazole introduced as an anti-flagellate
  • (a) alkylate DNA and inhibit DNA synthesis → strang breakage
  • (b) good against obligate anaerobes 
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